摘要
目的探讨肾透明细胞癌(clear cell renal cell cancer,CRCC)与乳头状肾细胞癌(papillary renal cell carcinoma,PRCC)混合性肾癌的诊治及预后。方法回顾性分析2007年至2017年我科收治的26例CRCC与PRCC混合性肾癌患者的临床诊治资料及预后随访情况。结果26例患者均经B超、CT检查明确诊断,18例行开放根治性肾切除术,7例行后腹腔镜下根治性肾切除术,1例行机器人辅助腹腔镜下肾肿瘤剜除术。手术均获成功,术后病理证实均为CRCC与PRCC的混合性肾癌。术后给予个体化治疗及随访,中位随访时间63个月,平均生存时间59.93个月,3年生存率83%,5年生存率73%。结论临床上CRCC与PRCC混合性肾癌少见,治疗以手术根治为主,术后治疗应个体化。患者的预后主要受临床和病理分期的影响,术后个体化治疗和随访也起重要作用。
Objective To explore the diagnosis and prognosis of mixed renal carcinoma with clear cell carcinoma and papillary cell carcinoma. Methods A retrospective analysis of 26 cases of mixed renal carcinoma with clear cell carcinoma and papillary cell carcinoma from 2007 to 2017 of our department was done. Results All 26 patients were diagnosed by B ultrasonic and CT examination clearly.Eighteen of them underwent open radical nephrectomy,seven patients underwent laparoscopic radical nephrectomy,and the rest one patient underwent robot assisted laparoscopic partial nephrectomy.The operations were all successful,and the postoperative pathology confirmed the diagnosis of mixed renal carcinoma with clear cell carcinoma and papillary cell carcinoma.The treatment and follow-up were given according to the individual situation.Their median follow-up period was63 months.Their mean survival was 59.93 months,and three-year survival rate and five-year survival rate were 83%and 73%respectively. Conclusions It is rare for patients with mixed renal carcinoma with clear cell carcinoma and papillary cell carcinoma.The patients should be treated with radical nephrectomy,and postoperative treatment should be individualized.The prognosis of patients was mainly affected by clinical and pathological stages,and the postoperative individual treatment and follow-up were also important.
出处
《现代泌尿生殖肿瘤杂志》
2017年第6期331-333,共3页
Journal of Contemporary Urologic and Reproductive Oncology
关键词
透明细胞癌
乳头状细胞癌
混合性肾癌
Clear cell carcinoma
Papillary cell carcinoma
Mixed renal carcinoma
