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某三甲医院2014—2016年多重耐药菌感染趋势变迁 被引量:31

The trend of Multiple drug-resistant Organism( MDRO) infection in a 3A Grade Hospital from 2014 to 2016
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摘要 目的分析某三甲医院3年多重耐药菌感染趋势,了解多重耐药菌种类及分布特点,探索下一阶段多重耐药菌防控工作关键点。方法监测2014年1月至2016年12月住院患者致病菌中检出多重耐药菌3 921株,分析多重耐药菌检出率、感染部位、重点部门多重耐药菌构成比等相关数据。结果医院多重耐药菌的检出率3年来呈逐渐下降的趋势,分别为40.36%、36.92%、28.47%,差异有统计学意义(X^2=122.563,P=0.001);多重耐药菌感染部位分布连续3年以呼吸道感染占首位,分别59.14%、60.96%、45.75%,差异有统计学意义(X^2=66.972,P=0.001);ICU检出多重耐药菌在全院检出科室分布中的构成比逐年下降,分别为30.54%、28.60%、25.78%,差异有统计学意义(X^2=7.000,P=0.030)。结论近年来社区检出多重耐药菌有增多的趋势,而本院多重耐药菌检出逐年下降,至2016年全院各科室检出多重耐药菌构成比分布趋于均匀,符合各专科细菌感染的特点,消除了多重耐药菌集中在医院感染高危科室检出率高的现象。 Objective To analyze the multiple drug - resistant Organism (MDRO) infection trend in a 3 A Grade Hospital in 3 years, to explore the characteristic of nosocomial MDRO infection and the pivotal prevention and control of MDRO. Methods The data of inpatients from January 2014 to December 2016 were analyzed. A total of 3 921 strains of MDRO were detected. The detection rates of MDRO, locations of infection, and nosocomial infection rates of the key de- partments were analyzed. Results Significant annually decreasing tendency was found on positive rate of MDRO, from 40. 66% to 28.47% ( X^2 = 122. 563, P = 0. 001 ). The positive rate of respiratory infections of nosocomial MDRO was the first in 3 years, and decreasing significantly from 60.96% to 45.75% ( X^2 =66. 972, P =0. 001 ). Constituent ratios of MDRO infection in ICU was significantly reduced from 30. 54% to 25.78% ( X^2 = 7. 000, P = 0. 030). Conclusion Ac- cording to the three years monitoring data, the current prevention and control measures are effective in general and should be maintained. Moreover, new measures should be explored.
出处 《广东医学》 CAS 2018年第1期107-110,共4页 Guangdong Medical Journal
基金 广东省科技计划项目(编号:2012B031800241)
关键词 耐药 趋势 感染 drug resistant trend infection
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