摘要
目的探讨目标导向液体治疗应用于ASAⅡ~Ⅲ级胶质瘤患者手术切除中对其术中血流动力学及脑氧饱和度的影响,为患者安全手术提供保障。方法回顾性分析86例ASAⅡ~Ⅲ级胶质瘤患者的临床手术情况,其中实施常规治疗者为对照组(43例),以目标导向液体治疗者为观察组(43例),记录两组患者手术前30 min(T_0)、麻醉诱导后15 min(T_1)、手术中60 min(T_2)、手术中120 min(T_3)、手术中180 min(T_4)及手术完成时(T5)时血流动力学各项指标、心指数(CI)及脑氧饱和度(rSO_2)变化情况。结果两组患者T_1~T_5时rSO_2水平均较T_0时明显升高,P<0.05;观察组患者T_2~T_5时CI值、r SO_2、CVP及MAP水平明显高于对照组,P<0.05。结论目标导向液体治疗应用于ASAⅡ~Ⅲ级胶质瘤患者手术切除中可有利于提高患者脑氧饱和度水平。
Objective To explore the application value of goal-directed fluid therapy for ASAIⅡgrade glioma patients treated with surgical resection,and the impact on hemodynamics and cerebral oxygen saturation,and to provide security for patients’safety during surgery.Methods Clinical operation of 86 patients with ASAⅡ~Ⅲglioma were retrospectively analyzed.Among them,routine treatment was performed in the control group（43 cases）.Target-oriented liquid therapy group was the observation group（43 cases）.Hemodynamic indicators,cardiac index（CI）and brain oxygen saturation（r SO_2）of the 2 groups 30 min before the surgery（T_0）,15 min（T_1）after anesthesia,60 min（T_2）during surgery,120 min（T_3）during surgery,180 min（T_4）during operation were measured.Results r SO_2levels of the 2 groups during T_1~T_5were significantly higher than those at T0,P0.05;CI value,r SO_2,CVP and MAP levels in the observation group during T_2~T_5were significantly higher than the control group,P0.05.Conclusion Goal-directed fluid therapy in ASAIⅡgrade glioma patients can improve r SO_2level in brain.
出处
《实用癌症杂志》
2017年第12期1958-1961,共4页
The Practical Journal of Cancer
关键词
胶质瘤
脑氧饱和度
目标导向液体
手术切除
Glioma
Brain oxygen saturation （rSO2）
Goal-oriented liquid
Surgery
