摘要
川崎病是一种急性、自限性及全身性的血管炎性疾病，目前病因及发病机制尚未完全清楚。大剂量丙种球蛋白联合阿司匹林是川崎病急性期的标准治疗方案，但丙种球蛋白耐药型川崎病的治疗目前仍存在争议。川崎病最主要的并发症是冠状动脉病变。冠状动脉病变的处理包括抗血小板、抗凝、溶栓、内科介入及外科冠状动脉旁路移植术等治疗。另外，对于川崎病的随访管理也同样重要。
Kawasaki disease （KD）is an acute, self-limited and systemic vasculitis. The etiology and pathogenesis of KD still remain unclear. High-dose intravenous immunoglobulin （IVIG）combined with aspirin is the standard regimen of KD in acute stage, but the treatment of KD patients who were unresponsive to initial IVIG therapy still remains controversial. The main complication of KD is coronary artery lesions. Treatments of coronary artery lesions included antiplatelet,anticoagulant,thrombolytic therapy ,percutaneous coronary interven- tions and coronary artery bypass grafting. In addition, follow-up and management of KD were also very impor- tant.
出处
《国际儿科学杂志》
2017年第11期757-760,764,共5页
International Journal of Pediatrics
关键词
川崎病
丙种球蛋白
冠状动脉病变
随访
Kawasaki disease
Intravenous immunoglobulin
Coronary artery lesions
Follow-up
