摘要
目的为更好地开展泌尿系结石临床研究,尝试构建DSCU泌尿系结石成分数据库。方法使用Microsoft Access数据库软件,制定DSCU数据库的字段,编写数据字典,创建表、表间关联、窗体,完成数据输入,进行数据清理,注重数据库质控和管理。对DSCU基线数据进行统计分析,并例举DSCU应用实例。结果建成DSCU数据库:2001年1月至2016年12月,共收录病例2 832例;时间跨度16年;男性2 084例,女性748例;中位发病年龄50(1~95)岁;包括肾结石802例,输尿管结石1 281例,膀胱结石457例,尿道结石56例。所有病例均行结石成分分析,结石类型按比例依次为草酸钙结石(74.4%)、磷酸钙结石(16.1%)、尿酸结石(8.3%)和磷酸镁铵结石(0.6%)、胱氨酸结石(0.5%)和蛋白质结石(0.1%)。301例有完整的血尿代谢性评估数据,尿pH值中位数6.0(5.0~9.0),尿钙中位数4.09(0.04~20.65)mmol/24h,尿磷中位数11.70(0.64~52.68)。利用DSCU已开展两项泌尿系结石临床研究。结论 DSCU数据库是一个时间跨度较长、病例数量较大、数据质量较高的结石成分数据库,有利于进一步开展泌尿系结石临床研究。
Objective To establish the Database of Stone Composition in Urolithiasis(DSCU)to facilitate clinical research in urolithiasis.Methods Fields,data dictionary,tables,table relations and forms of DSCU were designed by Microsoft Access.The baseline statistics of DSCU were reported after data input and data clean.Examples of DSCU application for clinical research were presented.Results DSCU enrolled2 832 urolithiasis patients from2001 to 2016,including 2 084 males and 748 females with a median age of 50(1~95)years at disease onset.The database included 802 cases of renal calculi,1 281 cases of ureteral calculi,457 cases of bladder calculi and56 cases of urethral calculi.Stone composition analysis showed that the majority of stones were calcium oxalate(74.4%),followed by calcium phosphate(16.1%),uric acid(8.3%),magnesium ammonium phosphate(0.6%)and cystine(0.5%).Metabolic evaluation performed in 301 patients with complete records showed that the median urinary pH was 6.0(5.0~9.0),the median urinary calcium was 4.09(0.04~20.65)mmol/24 h and the median urinary phosphate was 11.70(0.64~52.68).Two clinical researches in urolithiasis had been finished based on the data of DSCU.Conclusion DSCU is a database of stone composition with long time span,large capacity and high quality.It is helpful for further clinical research of urolithiasis.
出处
《现代泌尿外科杂志》
CAS
2017年第11期831-834,共4页
Journal of Modern Urology
基金
上海市医学重点专科基金(No.ZK2015B04)
上海市科委自然科学基金(No.14ZR1432900)
关键词
数据库
尿路结石
结石成分
应用
临床研究
database
urolithiasis
stone composition
application
clinical research
