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两种药物用于肛周脓肿手术后伤口愈合情况的临床比较

Effect of benzalkonium chloride and povidone-iodine on postoperative perianal abscess in the healing of raw surface
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摘要 目的比较苯扎氯铵和碘伏用于肛周脓肿术后创面愈合情况的临床效果。方法将2016年收治的60例行肛周脓肿切开引流术的患者随机分为两组,观察组和对照组。观察组于术后第1天开始使用苯扎氯铵换药治疗,同时对照组使用碘伏换药,观察两种消毒剂的疗效、创面细菌菌落数、肉芽生长速度、创面愈合时间及并发症发生率。结果苯扎氯铵组总有效率为96.67%,碘伏组总有效率为83.33%,苯扎氯铵组的创面细菌菌落数、肉芽生长速度、创面愈合时间、并发症发生率方面均明显优于碘伏组,上述指标组间差异均具有统计学意义(P<0.05)。结论与碘伏相比,苯扎氯铵有较强的杀菌、控制局部感染作用,能加速创面的愈合,且对皮肤无刺激性,利于肛周脓肿术后创面愈合。 Objective To compare the effect of benzalkonium chloride and povidone-iodine on postoperative perianal abscess in the healing of raw surface. Methods Totai 60 cases with perianal abscess in our hospital 2016 were randomly divided into two groups, observation group and control group. The observation group wastreatedwith benzalkonium chloride, while the control group wastreatedwith povidone-iodine. The effects of two kinds of disinfectants, numbers of bacterial colonies, wound granulation growth rate, wound healing time and the incidence of complications were observed. Results The total effective rate was 96.67% in the observation group and 83.33% in the control group, numbers of bacterial colonies, wound granulation growth rate, wound healing time and the incidence of complications in the observation group were better than the control group. There were statistically significance (P 〈 0.05 ). Conclusion Comparedwithpovidone-iodine, benzalkonium chloride has a strong bactericidal control on the local infection, accelerates wound healing and has non- irritating to the skin. It is beneficial to the healing of raw surface after perianal abscess.
作者 裴平 王岩
出处 《中国处方药》 2017年第11期133-134,共2页 Journal of China Prescription Drug
关键词 苯扎氯铵 碘伏 感染 创面愈合 Benzalkonium chloride Povidone-iodine Infection Wound healing
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