摘要
目的分析持续泵注不同剂量右美托咪定在缓解食管癌手术患者麻醉苏醒期副作用中的作用.方法随机选取68 例食管癌手术患者,将其平均分为观察组与对照组,并给予两组患者不同的右美托咪定持续泵注剂量,其中,观察组的持续 泵注剂量为0. 2ug/kg/hr,对照组则为0. 4 ug/kg/hr,分别观察两组患者麻醉苏醒期间的 MAP、 HR、苏醒时间、躁动与镇静 情况,结果 观察组于入苏醒室时、拔管即时以及拔管后5mm三个时间点的 MAP与 HR值均优于对照组;观察组的麻醉苏 醒时间、躁动评分以及镇静评分等各项临床指标均优于对照组,组间差异检验值均为 P〈0. 05,组间数据差异均具有统计学 意义,结论给予食管癌手术患者适宜的右美托咪定持续泵注剂量,不仅能有效缓解麻醉苏醒期间患者机体所产生的副作 用,还能有效缓解患者的术后躁动症状.
Objective To investigate the effect of dexmedetomidine in relieving side effects of anesthesia in patients un-derwent esophageal cancer surgery. Methods A total of 68 patients underwent esophageal cancer surgery were divided into the observation group and control group？ 34 cases in each group. The observation group received 0. 2ug/kg/hr of continuous injec-tion. The control group was treated with 0. 4ug/kg/hr of continuous injection. The MAP, HR, awakening time, restlessness and sedation were observed in the two groups. Results MAP and HR in the observation group were better than those in the control group at three times points： the time of entering the recovery room, immediate extubation and extubation after 5 mi-nutes （P〈C〇. 05）. The anesthesia awakening time, restlessness score and sedation score and other clinical indicators in the ob-servation group were better than those in the control group （P〈0. 05）. Conclusion Continuous dexmedetomidine infusion can effectively alleviate the side effects during the anesthesia awakening, and alleviate the restlessness after surgery.
出处
《临床研究》
2017年第9期22-23,共2页
Clinical Research
关键词
持续泵注
不同剂量
右美托咪定
食管癌手术
麻醉苏醒期
Continuous injection
different doses
dexmedetomidine
esophageal cancer surgery
anesthesia recovery period
