摘要
目的探讨实时剪切波弹性成像(SWE)技术在检测健康儿童肝组织硬度中的应用价值。方法对243名正常健康儿童行SWE检查,测量肝脏硬度值(LSM),比较不同性别及肝段间LSM差异。根据年龄将243名儿童分为学龄前期组、学龄期组、青春期组,比较3组间LSM差异。对不同操作者测量值行一致性分析。结果正常儿童LSM均值为(4.21±0.70)kPa,95%可信区间为(4.11,4.31)kPa;肝S5段的取样成功率高于S4段[(100%(243/243)vs 79.83%(194/243)],S5段LSM平均值[(4.07±0.71)kPa]低于肝S4段[(4.49±0.95)kPa],差异有统计学意义(P<0.01);LSM随年龄增长有增高趋势,男童LSM较女童稍高,差异均无统计学意义(P均>0.05)。不同操作者测值一致性非常好,组内相关系数为0.92。结论 SWE可客观、定量评估儿童肝脏硬度。
Objective To explore the clinical value of real-time shear wave elastography（SWE）in liver tissue stiffness of normal children.Methods Totally 243 normal children were examined by SWE.The data of liver stiffness measurement（LSM）were recorded and analyzed.The differences of LSM between different genders and hepatic segments were compared.According to the age,243 normal children were divided into pre-school group,school age group and adolescent group;and the differences of LSM between 3groups were compared.The consistency was analyzed in different operators.Results The mean value of LSM in normal children was（4.21±0.70）kPa,and the 95% confidence interval was（4.11,4.31）kPa.The success rate of segment S5 was higher than that of segment S4（100% [243/243]vs 79.83% [194/243]）,and the mean value of LSM in segment S5 was lower than that in segment S4（P〈0.05）.The mean value of LSM increased with age,and the boys＇ was a slightly higher than the girls＇,but there were no statistical differences between them（all P〉0.05）.LSM had good consistency in different operators,the intraclass correlation coefficient was 0.92.Conclusion SWE could be an objective and quantitative assessment in liver stiffness of children.
出处
《中国医学影像技术》
CSCD
北大核心
2017年第9期1353-1356,共4页
Chinese Journal of Medical Imaging Technology
关键词
剪切波弹性成像
肝脏硬度
儿童
超声检查
Shear wave elastography
Liver stiffness
Child
Ultrasonography
