摘要
目的探讨补肾活血汤联合经皮椎体后凸成形术(PKP)治疗老年骨质疏松性椎体压缩性骨折的临床效果,以寻求该病的有效治疗方法。方法选择老年骨质疏松性压缩性骨折患者174例,采用随机数字表法分为观察组和对照组,每组87例。2组均给予PKP治疗,对照组术后给予钙尔奇和阿法骨化醇治疗,观察组在对照组治疗的基础上给予补肾活血汤治疗。观察2组术前、术后1、3和6个月视觉模拟疼痛评分(VAS);术前和术后6个月矢状面Cobb角、伤椎前缘高度比;腰椎2~4、股骨颈、Wards三角和全髋的骨密度;2组患者术后6个月内再次骨折发生率。结果与对照组比较,术后3个月和6个月观察组VAS评分均显著降低(均P<0.05);观察组术后6月Cobb角均显著低于对照组(P<0.05),伤椎前缘高度比显著高于对照组(P<0.05)。与对照组比较,观察组术后6个月腰椎2~4、股骨颈、Wards三角区和全髋骨密度均显著升高(均P<0.05)。观察组术后6个月内再次椎体压缩性骨折的发生率显著低于对照组(P<0.05)。结论补肾活血汤联合PKP治疗骨质疏松性压缩性骨折可增加骨密度,降低疼痛程度,增加椎骨稳定性,降低骨折再发生率,有助于改善PKP远期预后,值得临床推广应用。
Objective To oberve the effect of Bushen Huoxue Decoction combined with percutaneous kyphoplasty（PKP） in the treatment of elderly patients with osteoporotic vertebral compression fractures.Methods 174 elderly patients with osteoporotic vertebral compression fractures were randomly divided into 2 groups：observation group and control group,87 in each;PKP was performed in both groups,and caltrate and alfacalcidol were administrated to patients in control group after operation while Bushen Huoxue Decoction to patients in observation group;observation was made in both groups,including the observation of the visual analogy scores（VAS） of the patients at the time point of before operation,1 month,3 months and 6 months after operation,the observation of sagittal Cobb angle,anterior height of the vertebral body,bone mineral density of lumbar 2 - 4,femoral neck,Wards triangle and total hip at the time point of before operation and 6 months after operation,and the observation of new fractures incidence within 6 months after operation.Results The VAS scores of the patients in observation group at the time point of 3 months and 6 months after operation dropped down obviously and were much lower than those of the patients in control group（P〈0.05）;the Cobb angle of the patients in observation group at the time point of 6 months after operation was significantly lower than that in control group（P〈0.05） while the anterior height of the vertebral body in observation group was significantly higher than that in control group（P〈0.05）;the bone mineral density of lumbar 2- 4,femoral neck,Wards triangle and total hip of the patients in observation group at the time point of 6months after operation were significantly higher than those in control group（P〈0.05）;the incidence of new fractures within6 months after operation in observation group was significantly lower than that in control group（P〈0.05）.Conclusions Bushen Huoxue Decoction combined with percutaneous kyphoplasty can increase bone density,relieve pain,strengthen vertebrae stability and reduce the incidence of recurrent fractures,it is of help in improving the long-term prognosis of PKP and is worthy of clinical application.
作者
刘波
吕刚
杨宏
Liu Bo Lyu Gang Yang Hong(Department of Orthopedics, Chengdu Integrated TMC＆ Western Medicine Hospital, Chengdu, Sichuan Province, 610000, P. R. China)
出处
《老年医学与保健》
CAS
2017年第3期216-219,共4页
Geriatrics & Health Care
关键词
老年
骨质疏松
骨折
补肾活血汤
经皮椎体后凸成形术
elderly
osteoporosis
fracture
Bushen Huoxue Decoction
percutaneous kyphoplasty（PKP）
