摘要
目的 观察卡人工泪液凝胶和羟糖甘滴眼液在干眼症的临床治疗中的疗效和安全性.方法 将浙江省永康市第一人民医院收治的干眼症患者按照其入院时所得到的编号单双情况分成CT和CL组,CL组予以卡波姆眼用凝胶治疗,CT组给予卡波姆眼用凝胶联合羟糖甘滴眼液治疗.评估2组患者的疗效、泪膜稳定性3项指标以及生活质量分值.结果 CT组临床疗效显著优于CL组（P〈0.05）,CT组泪膜破裂时间（BUT）、泪液分泌试验（SIT）显著优于CL组（P〈0.05）,角膜染色试验（FLT）显著比CL组短（P〈0.05）;在治疗后7d、14d、28d这几个时间点,CT组的生活质量分值均显著高于CL组（P〈0.05）.结论 对干眼症患者同时使用卡波姆眼用凝胶和羟糖甘滴眼液两种药物能够显著减轻其临床症状,值得临床应用.
Objective To observe the efficacy of carbomer eye gel combined with hydroxycitron eye drops in the treatment of dry eye.Methods214 cases with xerophalmi in Yongkang first people＆#39;s hospital were divided into the CT group and the CL group according to the admission of odd and even numbers.The CL group were given carbomer eye gel, and the CT group were given carbomer eye gel combined with hydroxycitron eye drops.The effect, 3 index of tear film stability and quality of life were evaluated in the two groups.ResultsThe effect in the CT group was significantly higher than that in the CI group （P〈0.05）.Tear break-up time（BUT） and schirmer test（SIT） in the CT group were significantly better than those in the CL group（P〈0.05）, Fluorescent Stain Test （FLT） in the CT group was lower than that in the CL group.After treatment, at the seventh day, the fourteenth day, the twenty-eighth day, the quality of life in the CT group was significantly higher than that in the CL group.ConclusionIt can significantly relieve the clinical symptoms which carbomer eye gel combined with Hypoglycemic eye drops Dextran 70 and Glycerol Eye Drop on the treatment of xerophthalmia, and it is worthy of promotion.
作者
蒋琦芳
胡美君
何锐
JIANG Qi-fang HU Mei-jun HE Rui(Department of Ophthalmology, the First People＇s Hospital of Yongkang City, Yongkang 321300, China)
出处
《中国生化药物杂志》
CAS
2017年第6期67-68,71,共3页
Chinese Journal of Biochemical Pharmaceutics
