摘要
综述了抗高血压药物替米沙坦化学合成方法的研究进展。对近年来国内外有关文献资料进行分析评述,对不同原料、不同中间体的合成方法进行对比分析,文献合成方法各有所长,但先进,可靠,成本低,收率高的方法尚需进一步研究。
The research progress in chemical synthesis of anti hypertensive drug telmisartan was introduced. Relevant literatures in recent years at home and abroad were analyzed, and synthesis methods with different materials and intermediates were compared, The results show that these synthesis methods in the literatures have their own strengths, but it is still very necessary to develop advanced and reliable synthesis method with low cost and high yield.
出处
《当代化工》
CAS
2017年第5期958-961,共4页
Contemporary Chemical Industry
基金
陕西中医药大学青年基金
项目号:2015QN22
关键词
替米沙坦
抗高血压
合成
Telmisartan
Anti hypertension
Synthesis