摘要
目的:探讨血清淀粉样蛋白A(serum amyloid A,SAA)检测在细菌感染和病毒感染中的早期诊断价值。方法:选择2015-05~06于我院就诊的细菌感染病例100例、病毒感染病例51例和健康体检者65例,检测受检者血清SAA、白细胞(WBC)、C-反应蛋白(CRP)、降钙素原(PCT)水平,分析各指标的组间差异,并应用受试者工作特征(receiver operating characteristic,ROC)曲线评价各指标对感染性疾病的诊断价值。结果:3组间SAA、WBC、CRP及PCT差异均有统计学意义(P<0.05),细菌感染组和病毒感染组的SAA、WBC、CRP、PCT水平均高于健康对照组。ROC曲线分析显示,SAA对病毒感染性疾病(曲线下面积0.900)和细菌感染性疾病(曲线下面积0.960)以及两者的鉴别(曲线下面积0.890)均有较高的诊断作用。结论:SAA对感染性疾病有较好的诊断意义,可作为感染性疾病早期诊断的又一个临床指标。
Objective：To investigate the value of serum amyloid A（SAA）detection in early diagnosis of bacterial infections and viral infections.Methods：From May to June in 2015,100 cases with bacterial infection,51 cases with viral infection and 65 healthy people in our hospital were detected serum specimens subjects SAA、WBC、CRP and PCT level,difference between the groups and receiver operating characteristic（ROC）curve was analyzed to evaluate the diagnostic value of the index on infectious diseases.Results：Differences of SAA、WBC、CRP and PCT among the three groups were statistically significant（P 〈0.05）,SAA、WBC、CRP and PCT of bacterial infection and viral infection group was higher than those of the control group.ROC curve showed SAA have a higher diagnostic role in viral infections（area under the curve0.900）and bacterial infections（area under the curve 0.960）and identification between both（area under the curve 0.890）.Conclusion：SAA has better diagnostic significance of infectious diseases,can be used as another clinical indicator in early diagnosis of infectious diseases.
出处
《西北国防医学杂志》
CAS
2017年第5期291-294,共4页
Medical Journal of National Defending Forces in Northwest China
基金
全军"十二五"面上课题资助项目(CWS11J205)
军队"十二五"重大专项子课题"师团检验箱组"资助项目(424135S)
