摘要
目的:研究DU(十二指肠溃疡)患者中医自拟方治疗的临床效果。方法:回顾分析我院自2008年8月至2013年8月以来,于我科治疗的115例DU患者临床资料,依据治疗方式将其分为研究组(n=60)、对照组(n=55),对照组应用兰索拉唑、阿莫西林、克拉霉素治疗,研究组基于对照组方案联合中医自拟方治疗,两组疗程均为4周。观察对比两组疗效,观察对比两组治疗前后的症状总积分,观察对比两组治疗后的中医症候评分,观察对比两组治疗期间的不良反应及6个月后的复发情况。结果:研究组痊愈29例,显效17例,有效12例,总有效率为96.67%,对照组痊愈20例,显效16例,有效9例,总有效率为81.82%,两组相较,呈明显差异(P<0.05)。研究组治疗前症状总积分与对照组相较,不具差异(P>0.05),治疗后症状总积分与对照组相较,呈明显差异(P<0.05)。研究组治疗后的中医症候评分中,嘈杂烧心、泛酸与对照组相较,不具差异(P>0.05),胃脘疼痛、胃胀、嗳气、善太息、纳差与对照组相较,均呈明显差异(P<0.05)。治疗期间,研究组、对照组均未出现毒副作用、药物过敏等不良反应,肝肾功能均未见异常表现。6月后,研究组1例复发,复发率为1.67%,对照组9例复发,复发率为16.36%,两组相较,呈明显差异(P<0.05)。结论:DU患者应用中医自拟方治疗,不仅能够显著改善临床症状,有助溃疡愈合、减少复发,而且不良反应少,无毒副作用,安全有效,应予推广。
Objective： To study the clinical effect of DU （duodenal ulcer） patient Chinese Decoction treatment. Methods： Retrospective analysis of our hospital from 2008 August to 2013 since August, clinical data of 115 cases of DU patients in our department for treatment, according to mode of treatment will be divided into the study group （n=60）, control group （n=55）, the control group of lansoprazole, amoxicillin, clarithromycin therapy, research the application of traditional Chinese medicine decoction treatment group, two groups were treated for 4 weeks. Two groups were observed and compared the curative effect of two groups were observed and compared before and after treatment, the symptom score were compared between two groups after treatment, TCM syndrome score, the recurrence of adverse reactions were observed in the two groups during treatment and 6 months after. Results： The study group 29 cases were cured, 17 cases markedly effective, effective in 12 cases, the total effective rate was 96.67%, control group 20 cases were cured, 16 cases markedly effective, effective in 9 cases, the total effective rate was 81.82%, compared with two groups, showed significant difference （P 〈 0.05）. Study group before the treatment and the control group compared with the symptom score, with no difference （P 〉 0.05）, after treatment of symptom score compared with the control group, showed a significant difference （P 〈 0.05）. The study group after treatment of TCM syndrome score in noisy heartburn, pantothenic acid, and the control group compared to, not the difference （P 〉 0.05）, epigastric pain, bloating, belching, good Taixi, anorexia and control group were compared, is significantly difference （P 〈 0.05）. During the treatment, the study group, the control group showed no toxic side effects, drug allergies and other adverse reactions, hepatic and renal function were normal performance. After June, the study group and 1 cases of recurrence, the recurrence rate was 1.67%, control group 9 cases of recurrence, the recurrence rate was 16.36%, compared with two groups, showed significant difference （P 〈 0.05）. Conclusion： The application of traditional Chinese medicine decoction for the treatment of patients with DU, not only can improve the clinical symptoms, help ulcer healing, reduce recurrence, and less adverse reaction, safe and effective, non-toxic side effects, should be popularized.
作者
高杰芳
高原
GAO Jie-fang GAO Ynan(Wulan chabn city center hospital in NeiMongol 012000)
出处
《内蒙古中医药》
2017年第5期47-48,共2页
Inner Mongolia Journal of Traditional Chinese Medicine
关键词
中医自拟方
症状
十二指肠溃疡
复发
不良反应
疗效
TCM Decoction
symptoms
duodenal ulcer
relapse
adverse reaction
curative effect
