摘要
目的对食管癌术后发生胃排空障碍的病例进行单中心分析,总结其发生原因和诊治经验。方法回顾性分析第二军医大学长征医院2003年1月至2012年12月间1 294例食管癌患者的病例资料,将其中发生胃排空障碍的19例(1.47%)患者作为观察组,未发生胃排空障碍的1 275例作为对照组。比较两组患者年龄、糖尿病史、吻合部位、手术入路及游离胃方式等,分析可能影响胃排空障碍发生的因素。通过本中心的研究得出胃排空障碍发生规律和治疗手段。结果术后发生胃排空障碍的19例患者经保守治疗均痊愈。经单因素分析显示,胃排空障碍的发生与患者的年龄、糖尿病史、吻合部位、手术入路和游离胃方式均无关(P>0.05)。结论食管癌术后胃排空障碍发生率低,发生原因不明确,一旦发生则严重影响患者的生活质量,但经保守治疗均可恢复。
Objective To analyze the cause, diagnosis and treatment of delayed gastric emptying （DGE） after esophagectomy in a single center. Methods The clinical data of 1 294 patients who underwent esophagectomy from Jan. 2003 to Dec. 2012 in Changzheng Hospital were retrospectively analyzed. Nineteen （1. 470/00） cases with DGE was included in the observation group and 1 275 cases with no delayed gastric emptying were taken as controls. The age, history of diabetes, anastomotic site, surgical approach, and disassociation of stomach were compared between the two groups, and the causes which may influence gastric emptying were analyzed. The rules and treatment of DGE were summarized. Results A total of 19 cases with DGE after esophagectomy were cured by conservative treatment in our study. Univariate analysis showed that age, history of diabetes, anastomotic site, surgical approach, and disassociation of stomach were not correlated with DGE after esophageetomy （P〉0. 05）. Conclusion The incidence rate of DGE after esophagectomy is low, with its causes remaining unclear. It directly affects patients＇ living quality and leads to delayed recovery, but can be cured by conservative management.
出处
《第二军医大学学报》
CAS
CSCD
北大核心
2017年第2期258-260,共3页
Academic Journal of Second Military Medical University
基金
国家自然科学基金(81101833)
上海市科委基金(14DZ1941306
16ZR1436900)
上海市青年医师培养计划(20120149)~~
关键词
食管癌切除术
胃排空障碍
胃瘫
手术后并发症
esophageal neoplasms
esophagectomy
delayed gastric emptying
gastroparesis
postoperative complications
