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尼莫地平辅助治疗难治性癫痫对患者的生活品质及认知功能的影响

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摘要 目的:分析尼莫地平对难治性癫痫的辅助治疗效果及其对患者的认知功能与生活品质的影响。方法:2013年1月-2016年6月,选取难治性癫痫患者90例,根据住院号奇偶随机分为两组各45例,其中对照组接受常规抗癫痫药物治疗,试验组在此基础上接受尼莫地平注射液静脉滴注治疗,连续2周后改用尼莫地平片口服维持治疗6个月;对比治疗前后两组的癫痫发作频率、认知功能与生活品质的差异。结果:与治疗前比较,两组治疗3、6个月后的癫痫发作频率明显减少,认知功能与生活品质明显改善(P〈0.05),且试验组的上述指标改善情况明显优于对照组(P〈0.05),差异有统计学意义。结论:尼莫地平可改善难治性癫痫患者的癫痫发作频率,提高患者的认知功能与生活品质,是本病较为理想的治疗方法。
出处 《癫痫与神经电生理学杂志》 2017年第1期31-32,40,共3页 Journal of Epileptology and Electroneurophysiology(China)
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