摘要
目的评价坐式八段锦练习对重度稳定期COPD患者气道炎性反应的影响。方法成立研究团队制订坐式八段锦锻炼计划,并按锻炼计划内容实施锻炼。6个月后检测患者痰液中炎性因子白细胞介素8、肿瘤坏死因子-α和C反应蛋白;中性粒细胞、淋巴细胞和巨噬细胞计数;肺功能情况,用力肺活量、第1秒用力呼气量、第1秒用力呼气量实测值占预计值的百分比、第1秒用力呼气量占用力肺活量的比值。结果两组患者痰液中炎性因子白细胞介素8、肿瘤坏死因子-α和C反应蛋白、中性粒细胞计数比较有统计学意义(P<0.01),淋巴细胞和巨噬细胞计数比较无统计学意义(P>0.05);用力肺活量、第1秒用力呼气量、第1秒用力呼气量实测值占预计值的百分比、第1秒用力呼气量占用力肺活量的比值比较有统计学意义(P<0.01)。结论坐式八段锦锻炼能改善重度稳定期COPD患者的气道炎性反应,提高肺功能。
Objective To evaluate the effect of Baduanjin of Sitting Style to the airway inflammatory response of patients with severe stable Chronic Ob- structive Pulmonary Disease （COPD）. Methods Research team was established, formulated and implemented the training program of Baduanjin of Sitting Style. After six months ,inflammatory factor interleukin - 8, tumor necrosis factor and C - reactive protein in the sputum was test, and to assay the count of neutrophils, lymphocytas and maerophages in the blood. Lung function was monitored through forced vital capacity （FVC） ,forced expiratory volume in first second （ FEV1 ）, FEV1% ,FEV1/FVC. Results The test results of inflammatory factor interleukin - 8 ,tumor necrosis factor and C - reactive protein in the sputum between two groups were statistically significant （P 〈 0.01 ）, and the comparison of lymphoeytes and macrophages in the blood were not statistically difference （P 〉 0. 05 ）. The score of FVC, FEV1, FEV1%, FEV1/FVC were statistically significance （ P 〈 0.01 ）. Conclusion Baduanjin of Sitting Style can improve the airway in- flammatory response of patients with severe stable COPD and enhance lung function.
出处
《护理管理杂志》
2017年第1期55-57,共3页
Journal of Nursing Administration
基金
湖南省教育厅科研项目(14C0846)
湖南省高层次卫生人才"225"工程项目资助(2013-13)
