摘要
癲是脑神经元同步异常放电导致的脑功能紊乱综合征,其反复发作可造成认知功能的损伤和行为的异常。静息态功能MRI(rs-fMRI)是一种血氧水平依赖功能MRI,可对大脑静息态下的自发活动进行研究。目前大量癲rs-fMRI的研究主要集中于成年病人,然而儿童癫的病因、发病机制及临床治疗等都与成人癫不尽相同。主要对近年来rs-fMRI在儿童癫静息态网络、认知功能障碍研究及其在儿童癫手术治疗方面的应用予以综述。
Epilepsy is a brain dysfunction syndrome which is caused bysynchronous abnormal discharge of brain neurons.Repeated seizures can cause cognitive function damage and abnormal behavior. Resting state functional MRI （rs-fMRI） is a kind of blood oxygenation level dependent functional magnetic resonance imaging, which can evaluatethe spontaneous activity of brain at resting state. Currently, a large number rs-fMRI research on epilepsy focus on adult patients, however, the epilepsy etiology, nosogenesis, clinical symptoms, EEG patterns, clinical treatment and prognosis inchildren are not same asthat of adults. This paper mainly summaries the research of rs-fMRI on resting state network in children with epilepsyorcognitive dysfunction, and its application in children who received surgical treatment forepilepsy.
作者
李武超
张体江
LI Wuchao ZHANG Tijiang(Department of Medical Imaging, Affiliated Hospital of Zunyi University, Zunyi 563003, China Department of Radiology, Guizhou Province People＇ s Hospital)
出处
《国际医学放射学杂志》
2017年第1期32-36,共5页
International Journal of Medical Radiology
基金
国家自然科学基金(81360218)
贵州省研究生工作站建设任务(黔教研合JYSZ字[2014]019)
贵州省普通高等学校创新团队建设任务(黔教合人才团队字[2014]37)
关键词
静息态功能磁共振成像
儿童
癫癎
静息态网络
认知功能障碍
手术
Resting state functional magnetic resonance imaging
Pediatric
Epilepsy
Resting state network
Cognitive dysfunction
Surgery
