摘要
目的采用全脑血管造影数据，制作颅内动脉瘤3D打印模型，并根据模型分析颅内动脉瘤的相关参数，为开颅手术提供实物参考。方法前瞻性选取自2016年5月1日至2016年6月30日浙江大学绍兴医院神经外科经数字减影血管造影（DSA）检查确诊的颅内动脉瘤11例，以DICOM格式输出3D—DSA数据，应用MIMICS软件进行格式转换，三维立体重建，选定目标区域后通过3D打印制作1：1和1：32种规格实物模型。结果3D打印的颅内动脉瘤模型能清晰显示脑血管和颅内动脉瘤大小、形状、瘤体朝向以及与载瘤动脉的关系和周围分支血管情况。在开颅动脉瘤夹闭手术中，1：1和1：3模型均能为手术提供良好的参考价值。结论3D打印技术应用于人体颅内动脉瘤模型制作，可为颅内动脉瘤诊治提供实物模型，可为术前、术中颅内动脉瘤瘤夹选择和夹闭方式提供参考。
Objective As the intracranial aneurysm diagnosed by digital subtraction angiography （DSA） examination, the patient＇s cerebral vessels models of intracranial aneurysms were built by 3D Printer. According to the models, the size, shape, orientation of the aneurysms, as well as the relationship between the parent artery and the branch vessels were analyzed to provide reference for craniotomy. Methods The 11 patients with intracranial aneurysms diagnosed by DSA were prospectively selected in this study from May 1, 2016 to June 30, 2016. The DSA data of the patients were output in DICOM format, after format conversion and three-dimensional reconstruction by MIMICS software, the selected target regions were modeled by 3D printers in different proportions （1：1 and 1：3）. Results The cerebral vascular 3D printing models could reflect the shape, size and distribution of the cerebral vascular and orientation of the intracranial aneurysms. It could also show the relationship between the aneurysm and parent arteries along with vascular branches. It was showed that the original size and different amplified model could provide reference for the aneurysm clipping surgery. Conclusion The 3D printing technology can be used into the production of human cerebral vascular models, which can provide a physical model for diagnosis and treatment of intracranial aneurysms, and it can also provide useful reference for preoperative and intraoperafive aneurysm clip selection and clamping method decision during the aneurysm clip surgery.
出处
《中华神经医学杂志》
CAS
CSCD
北大核心
2017年第1期75-77,共3页
Chinese Journal of Neuromedicine
基金
绍兴市科技局公益性技术应用研究计划项目（2015B70052）
关键词
3D打印
颅内动脉瘤
开颅夹闭手术
Three D printing
Intracranial aneulysm
Endovascular coiling clipping
Coiling
