摘要
目的探讨鼻咽癌患者放疗前牙面用氟保护剂预防放疗后放射性龋齿的效果。方法选择首次接受放疗的鼻咽癌患者112例,采用自身对照方法分为氟保护剂组和生理盐水组。在放疗前1、3、5 d开始试验,每次清洁牙面,消毒干燥后,用小毛刷将氟保护剂涂抹在一侧牙面(氟保护剂组),同时将生理盐水涂抹在另一侧牙面(生理盐水组),观察并记录放疗前和放疗后1 a 2组的龋失补牙数(DMFT)和龋失补牙面数(DMFS)。结果放疗前,氟保护剂组和生理盐水组DMFT和DMFS比较差异均无统计学意义(P均>0.05)。与放疗前比较,2组DMFT和DMFS在放疗后1 a均明显升高(P均<0.05),但生理盐水组DMFT和DMFS升高更为明显,且生理盐水组DMFT和DMFS明显高于氟保护剂组(P<0.05)。结论鼻咽癌患者放疗前牙面用氟保护剂能显著降低放射性龋齿的发生。
Objective To explore the preventive effect of fluor protector for radioactive decay in the radiotherapy of nasopharynx cancer. Methods The 112 patients with nasopharynx cancer received radiotherapy were divided into the fluor protector group and the sodium chloride group by self-control method. The test began in 1,3,5 d before radiotherapy. Fluor protector and sodium chloride were coated on the tooth surface after cleaning,disinfecting and drying the tooth surface every time. The decayed-missing-filled tooth（ DMFT） and decayed-missing-filled surface（ DMFS） were examined before and one year after the radiotherapy. Results Before the radiotherapy,the DMFT and DMFS of the two groups showed no significant difference（ P〈0. 05）. However,one year after the radiotherapy,DMFT and DMFS of the two groups increased significantly（ P 0. 05） and more increase was found in the sodium chloride group（ P 0. 05）. The DMFT and DMFS of the sodium chloride group were more greater than those of the fluor protector group（ P 0. 05）. Conclusion Fluor protector could significantly reduce the occurrence of radioactive decay in the radiotherapy of nasopharynx cancer.
出处
《肿瘤基础与临床》
2016年第5期411-413,共3页
journal of basic and clinical oncology
关键词
氟保护剂
放射性龋齿
龋失补牙数
龋失补牙面数
fluor protector
radioactive decay
decayed-missing-filled tooth
decayed-missing-filled surface
