摘要
目的分析新柏压液基细胞学技术分析(TCT)联合高危型HPV病毒筛查在临床宫颈癌筛查中的应用价值。方法选择2014年1月至2015年12月期间于本院接受宫颈癌筛查的300例女性为研究对象,分别采用阴道镜下宫颈组织病理活检、TCT检查及高危型HPV病毒筛查以及后二者联合检查的方法,以病理活检结果为检查"金标准",计算TCT检查与高危型HPV病毒筛查以及二者联用诊断结果的准确性、灵敏度和特异性。结果对照病理活检结果发现,单用TCT检查准确性、灵敏度、特异性分别为80.00%、74.80%、83.82%、单用高危型HPV病毒筛查结果准确性、灵敏度、特异性分别为75.67%、87.40%、67.05%,二者联用与病理结果相比检查准确性、灵敏度、特异性分别为99.67%、99.21%、100.00%,差异显著,具有统计学意义,P<0.05。结论相比单用TCT检查、高危型HPV病毒筛查,二者联用在宫颈癌的筛查中显著提高宫颈癌筛查的准确性、灵敏性与特异性,显著提高临床确诊率,临床具有较高的应用价值。
Objective To analyze the application value of TCT combined with high risk HPV virus screening in clinical cervical cancer screening. Methods 300 cases of women received cervical cancer screening in our hospital from January 2014 to December 2015,respectively accepted the colposcopic cervical tissue biopsy,TCT and high-risk type HPV screening to biopsy results for check the ＂ gold standard＂,calculation of TCT and high risk HPV screening and combined with the accuracy, sensitivity, specificity of diagnosis. Results Compared with the pathological biopsy results found that TCT check the accuracy,sensitivity and specificity were80. 00%, 74. 80, 83. 82%, single with high-risk HPV screening results accuracy, sensitivity, specificity respectively 75.67%,87.40%,67.25%,combined with and pathological results compared to check the accuracy,sensitivity,specificity, respectively 99. 67%,99. 21% and 100. 00%, significant difference had statistical significance,P〈0. 05. Conclusions Compared with TCT,high-risk HPV screening,the two combined with significantly improve cervical cancer screening accuracy,sensitivity and specificity in the screening of cervical cancer,and can significantly improve the rate of clinical diagnosis,with higher clinical application value.
作者
穆迎娟
高宇琳
刘彦慧
Mu Yingiuan et al(Maternal and Child Health Care Hospital, Dongguan 523000, Chin)
出处
《齐齐哈尔医学院学报》
2016年第28期3562-3564,共3页
Journal of Qiqihar Medical University
