摘要
目的：探讨MRI在产前诊断胎儿唇腭裂畸形中的临床作用。方法：回顾性分析2013年12月-2015年9月进行影像检查发现的11例胎儿唇裂或腭裂畸形的孕妇的影像学资料,孕周23-31周。MRI检查序列包括快速稳态平衡梯度回波（B-FFE）序列、单次激发快速自旋回波（SSFSE）序列,行横轴面、矢状面及冠状面扫描,重点行横轴面、冠状面扫描观察胎儿唇腭部形态结构,矢状面观察继发腭是否有中断、缺失,将产前MRI、超声结果与随访结果进行对照分析。结果：产前超声诊断单纯唇裂4例;唇裂但腭裂不确定5例,2例唇裂合并腭裂。MRI诊断单纯唇裂1例,唇裂合并上颌骨牙槽突弯曲2例、牙槽突裂1例,唇裂合并腭裂7例。引产结果与产前MRI诊断均一致。超声诊断的4例单纯唇裂中,经MRI诊断为唇裂合并腭裂2例、唇裂合并牙槽突裂1例,另1例与超声诊断一致。超声诊断的5例唇裂但腭裂不确定中,MRI诊断为唇裂合并腭裂4例,另1例为唇裂合并上颌骨牙槽突弯曲。超声诊断的2例唇裂伴腭裂中,经MRI诊断为唇裂伴上颌骨牙槽突弯曲但无腭裂1例,另1例与超声诊断一致。结论：MRI在诊断胎儿唇腭裂畸形中相对于超声可提供更多有用的诊断价值,可作为产前超声诊断的有效补充方法之一。
Objective：To study the clinical application value of MRI in the diagnosis of fetal cleft lip and palate deformities. Methods： Imaging materials of 11 cases with fetal cleft lip and palate deformities diagnosed according to imaging examination between December 2103 and September 2015 were retrospectively analyzed. The gestational period was 23w to 31w. MRI sequences included balanced fast field echo （B-FFE）,single-shot fast spin echo （SSFSE）,transverse, sagittal and coronary plane scanning. Axial and coronal plane were mainly used to display the morphology and structure of fetal lip and palate and sagittal plane was used to display any disruption or absence of palate. The prenatal MRI and ultrasonographic diagnosis were compared with that of follow-up and analysis was performed. Results：The prenatal ultrasonographic diagnosis were simple cleft lip （4 cases） ,cleft lip with indefinite cleft palate （5 cases） ,cleft palate associated with cleft lip （one case）. The MRI diagnosis were simple cleft lip （one case）,cleft lip associated with curve maxilla alveolar process （2 cases）, cleft alveolar process （one case）, cleft lip in combination with cleft palate （7 cases）. The resulted assessed after induced labor were in consistent with all of that in prenatal MRI diagnosis. Of the 4 cases had the ultrasonic diagnosis as simple cleft lip, the MRI diagnosis were cleft lip associated with cleft palate （2 cases）,cleft lip associated with cleft alveolar process （one case） ,another was in consistent with the ultrasonic diagnosis. Of the 5 cases had the ultrasonic diagnosis as cleft lip associated with indefinite cleft palate,4 cases diagnosed on MRI as cleft lip with cleft palate,and the other one had cleft lip in combination with curve alveolar process. Of the 2 patients with cleft lip with cleft palate diagnosed on ultrasonography, MRI diagnosis was cleft lip with curve maxilla alveolar process yet without cleft palate in one case,the other was in consistent with the ultrasonic diagnosis. Conclusion.. MRI,compared with ultrasonography,provides more useful information in the diagnosis of fetal cleft lip and palate deformities, which could be used as one of the effective supplemental method of prenatal ultrasound diagnosis.
作者
李旭
胡克非
LI Xu HU Ke-fei.(Department of Radiology, Anhui Provincial Children＇s Hospital, Hefei 230051 ,China)
出处
《放射学实践》
北大核心
2016年第11期1084-1088,共5页
Radiologic Practice
关键词
产前诊断
胎儿
磁共振成像
唇腭裂
Prenatal diagnosis
Fetus
Magnetic resonance imaging
Cleft lip and cleft palate
