摘要
目的 探讨晚餐-睡眠间隔时间和晚餐后散步与胃癌的关系.方法 收集胃癌病例428例,同期选取年龄、性别匹配的健康对照441例.通过问卷调查研究对象的人口学特征、晚餐-睡眠间隔时间和晚餐后散步等生活行为习惯.结果 较短的晚餐-睡眠间隔时间可增加胃癌的发病风险（ORadjusted=2.858,95％ CI：1.893 ～4.314）,晚餐后无散步相比散步胃癌的发生风险增加（OR =2.909,95％ CI：2.037 ～4.153）.较短的晚餐-睡眠间隔时间且餐后无散步患胃癌的危险性比较长间隔时间且散步的大（OR=6.427,95％ CI：3.964 ～ 10.419）.晚餐-睡眠时间与晚餐后散步乘积项（ORadjusted=1.572,95％ CI：1.361～ 3.769）,交互作用系数为3.273.结论 较短的晚餐-睡眠间隔时间和晚餐后无散步与胃癌发生具有关联且两者之间的交互作用可增加胃癌的发病风险.
Objective To investigate the relationship between dinner-to-bed time,post-dinner walk and gastric cancer （GC）.Methods 428 newly diagnosed GC patients and 441 age and gender matched healthy controls were recruited from local residents.A self-designed questionnaire was used to collect information including basic demographic characteristics,dinner-to-bed time interval and post-dinner walk etc.Results Shorter dinner-to-bed time was significandy associated with an increased risk of GC（ORadjusted =2.858,95% CI：1.893-4.314）.Non post-dinner walk was associated with increased risk of GC as compared with post-dinner walk（OR =2.909,95% CI：2.037-4.153）.The risk of GC individuals with shorter dinner-to-bed time and no post-dinner walk caused higher risk than those with longer dinner-to-bed time and post-dinner walk（OR =6.427,95% CI：3.964-10.419）.The product of dinner-to-bed time and post-dinner walk was （ORadjusted =1.572,95% CI：1.361-3.769） and the interaction index was 3.273.Conclusions The study suggests that both shorter dinner-to-bed time and no post-dinner walk are strong risk factors of GC,also the interaction of dinner-to-bed time and post-dinner walk significantly increase the risk of GC.
出处
《中华疾病控制杂志》
CAS
CSCD
北大核心
2016年第10期1004-1007,共4页
Chinese Journal of Disease Control & Prevention
基金
国家临床重点专科建设项目(国卫办医函[2013]544号)
关键词
胃肿瘤
问卷调查
病例对照研究
Stomach neoplasms
Questionnaires
Case-control studies
