三氧化二砷对大鼠血管平滑肌细胞凋亡及其表型和增殖细胞核抗原表达的影响
摘要
三氧化二砷(As2O3)是中药砒霜的主要成分,其在临床应用已有2400多年的历史。20世纪70年代,中国血液内科医师开始用As2O3治疗早幼粒细胞白血病,获得成功;随后该药也被用于实体肿瘤的治疗,其作用机制为抑制细胞周期、促进细胞凋亡、促进细胞分化、抑制血管新生等。
出处
《上海医学》
CAS
CSCD
北大核心
2016年第9期561-563,I0002,共4页
Shanghai Medical Journal
基金
国家863项目(2007AA02Z450)
四川省卫生厅科研项目(100466)资助
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共引文献2
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