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培美曲塞或多西他赛联合顺铂治疗晚期非小细胞肺癌的效果比较

Comparison of the Effect of Pemetrexed or Docetaxel Combined With Cisplatin in Treatment of Advanced Non-small Cell Lung Cancer
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摘要 目的探讨培美曲塞+顺铂、多西他赛+顺铂治疗晚期非小细胞肺癌的效果。方法将我院收治的晚期非小细胞肺癌患者40例根据治疗方式分为对照组和观察组各20例,观察两组患者的治疗效果。结果两组患者总有效率对比差异无统计学意义(P>0.05)。结论培美曲塞+顺铂、多西他赛+顺铂治疗晚期非小细胞肺癌的效果相当,但是培美曲塞+顺铂治疗安全性更高。 Objective To investigate the effect of pemetrexed + cisplatin and docetaxel + cisplatin in the treatment of advanced non-smal cel lung cancer. Methods 40 patients with advanced non-smal cel lung cancer were divided into the control group and the observation group of 20 cases according to the treatment method,the treatment effect of the two groups were observed. Results Two groups of patients with total efficiency comparing the difference was not statisticaly significant(P〉0.05).Conclusion Pemetrexed+cisplatin,docetaxel+cisplatin in the treatment of advanced non smal cel lung cancer is quite,but pemetrexed plug + cisplatin therapy is more safe.
作者 戴新
出处 《中国卫生标准管理》 2016年第17期119-120,共2页 China Health Standard Management
关键词 培美曲塞 顺铂 多西他赛 非小细胞肺癌 Pemetrexed Docetaxel Cisplatin Non-smal cel lung cancer
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  • 1郝学志,张湘茹,胡兴胜,王彬,赵龙妹,黄镜.培美曲塞治疗19例复发性晚期非小细胞肺癌[J].中国癌症杂志,2007,17(7):575-577. 被引量:35
  • 2孙燕,石远凯.临床肿瘤内科手册[M].第5版,北京:人民卫生出版社,2008:711-717.
  • 3Ohe Y. Chemoradiotherapy for lung cancer[ J]. Expert Opin Phar- macother, 2005,6(16) :2793-2804.
  • 4Fossella F, Pereira JR, van Pawel J, et al. Randomized, multina- tional, phase I study of docetaxel plus platinum combinations ver- sus vinorelbine plus cisplatin for advanced non-small-cell lung cancer: the TAX 326 study group [ J]. J Clin Oncol, 2003,21 (16) :3016-3024.
  • 5Scagliotti GV, Parikh P, yon Pawel J, et al. Phase m study com- paring cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive pa tients with advanced-stage non-small-cell lung cancer[J]: J Clin Oncol, 2008,26(21 ) :3543-3551.
  • 6Scagliotti GV, Kortsik C, Dark GG, et al. Pemetrexed combined with oxaliplatin or carboplatin as first-line treatment in advanced non-small cell lung cancer: a multicenter, randomized,phase 1/ trial[J]. Clin Cancer Res, 2005,11(2 Pt 1) : 690-696.
  • 7Zinner RG, Fossella FV, Gladish GW, et al. Phase 11 study of pemetrexed in combination with carboplatin in the first-line treal- ment of advanced nonsmall cell lung cancer [ J ]. Cancer, 2005, 104( 11 ) :2449-2456.
  • 8Scagliotti GV, Park K, Patil S, et al. Survival without toxicity for cisplatin plus pemetrexed versus cisplatin plus gemcitabine in che- monaive patients with advanced non-small cell lung cancer: a risk- benefit analysis of a large phase I study [ J ]. Eur J Cancer, 2009,45 ( 13 ) :2298-2303.
  • 9Greenhalgh J, McLeod C, Bagust A, et al. Pemetrexed for the ma- intenance treatment of locally advanced or metastatic non-small cell lung cancer[ J ]. Health Technol Assess, 2010,14 ( Suppl 2) : 33- 39.
  • 10Hainsworth JD, Cebotam CL, Kanarev V, et al. A phase l/ , open-label, randomized study to assess the efficacy and safety of AZD6244 (ARRY-142886) versus pemetrexed in patients with non-small-cell lung cancer who have failed one or two prior chemo- therapeutic regimens [ J ]. J Thorac Oncol, 2010,5 ( 10 ) : 1630- 1636.

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