摘要
目的 通过共词分析的方法探讨我国2013年1月~2016年1月骨髓增生异常综合征（MDS）的研究进展,从而得出我国目前在MDS领域的研究热点和方向。方法 将“骨髓增生异常综合征”“MDS”作为关键词,在中国知网（CNKI）上检索2013年1月~2016年1月期间发表的关于MDS的文章,并将关键词导入Excel 2013进行统计与分析,然后通过Ucinet 6.0及Netdraw绘制共现分析图,从而显示出高频关键词之间的共篇关系。结果 按照本研究设置的纳入排除标准筛选文献,有481篇文章符合标准并纳入研究,提取高频关键词22个（T≥12）,主要集中于疾病特点、发病机制、疾病治疗等方面,由共现分析图可知,遗传学、地西他滨、去甲基化治疗等与MDS关系最为密切。结论 目前我国MDS在发病机制、疾病诊断、治疗方法等方面获得了较多新的研究成果,但对于疾病的发病机制的深入探讨、治疗方案的优化选择等方面有待于进一步研究。
Objective To study the research progress of myelodysplastic syndrome （MDS） from January 2013 to January 2016 using the co-word analysis, to discuss and summarize the hotspot and trend about MDS in China. Methods All the relevant articles that published in Chinese National Knowledge Infrastructure （CNKI） were researched from January 2013 to January 2016 with key words ＂myelodysplastic syndrome MDS＂. All of the key words were statistically analyzed by Microsoft Office Excel 2013 and revealed the relationship between the high-frequency key words through Ucinet 6.0 and Netdraw. Results 481 papers met the criteria and were selected in this research. 22 high-frequency key words were extracted （T ≥ 12）. The high-frequency key words concentrated on etiology, clinical features and treatments. By depicting the co-occurrence analysis chart, genetic, Decitabine and hypomethylated treatment were closely connected with MDS. Conclusion There are many new achievements about MDS in etiology, diagnosis, and treatments, however, more accurate etiology, optimal treatment will be new hotspots and trend in future.
出处
《中国医药导报》
CAS
2016年第26期176-180,共5页
China Medical Herald
