Single-cell RNA-seq technology lends a hand into HSC ontogeny
Single-cell RNA-seq technology lends a hand into HSC ontogeny
摘要
Hematopoietic stem cells（HSCs）are rare populations in the bone marrow of adult mammals which produce millions of blood cells for daily circulation by balancing self-renewal and multi-lineage differentiation.In vertebrates,a subset of
Hematopoietic stem cells(HSCs)are rare populations in the bone marrow of adult mammals which produce millions of blood cells for daily circulation by balancing self-renewal and multi-lineage differentiation.In vertebrates,a subset
参考文献5
-
1Ditadi A., Sturgeon C.M., Tober J., Awong G., Kennedy M., Yzaguirre A.D., Azzola L., Ng E.S., Stanley E.G., French D.L., Cheng X., Gadue P., Speck N.A., Elefanty A.G., Keller G.. Human definitive haemogenic endothelium and arterial vascular endothelium represent distinct lineages. Nat Cell Biol, 2015, 17: 580-591.
-
2Qian P., He X.C., Paulson A., Li Z., Tao F., Perry J.M., Guo F., Zhao M., Zhi L., Venkatraman A., Haug J.S., Parmely T., Li H., Dobrowsky R.T., Ding W.X., Kono T., Ferguson-Smith A.C., Li L.. The Dlk1-Gtl2 Locus Preserves LT-HSC Function by Inhibiting the PI3K-mTOR Pathway to Restrict Mitochondrial Metabolism. Cell Stem Cell, 2016, 18: 214-228.
-
3Orkin S.H., Zon L.I.. Hematopoiesis: An Evolving Paradigm for Stem Cell Biology. Cell, 2008, 132: 631-644.
-
4Tang, F., Lao, K., and Surani, M.A. Development and applications of single-cell transcriptome analysis. Nat Methods 8, S6–S11.
-
5Zhou F., Li X., Wang W., Zhu P., Zhou J., He W., Ding M., Xiong F., Zheng X., Li Z., Ni Y., Mu X., Wen L., Cheng T., Lan Y., Yuan W., Tang F., Liu B.. Tracing haematopoietic stem cell formation at single-cell resolution. Nature, 2016, 533: 487-492.
-
1Jialong Liang,Wanshi Cai,Zhongsheng Sun.Single-Cell Sequencing Technologies: Current and Future[J].Journal of Genetics and Genomics,2014,41(10):513-528. 被引量：21
-
2Li Wenquan,Huang Xianmang,Chen Qinghua,Zheng Airong,Wang Xian,Cai Agen (1. Department of Oceanography, Institute of Subtropical Oceanography, Xiamen University, Xiamen 361005, China).Study of effects of environmental factors on biochemical compositions of four species of marine single-celled algae[J].Acta Oceanologica Sinica,2000,19(1):69-77.
-
3王晓,李蔚,段芳龄.骨髓间充质干细胞多能性的研究进展[J].胃肠病学和肝病学杂志,2003,12(1):14-16. 被引量：2
-
4LI Xiao-hong,ZHU Jie-ning,JIANG Xue-yan,DENG Chun-yu,KUANG Su-juan,ZHANG Guang-feng,FU Yong-heng,YU Xi-yong.Vitamin C maintaining bone marrow mesenchymal stem cell self-renewal[J].South China Journal of Cardiology,2011,12(1):35-39.
-
5ZHAO Meng,LI LinHeng.Regulation of hematopoietic stem cells in the niche[J].Science China(Life Sciences),2015,58(12):1209-1215. 被引量：6
-
6Xi-Xi Chen,Fan Bai.Single-cell analyses of circulating tumor cells[J].Cancer Biology & Medicine,2015,12(3):184-192. 被引量：4
-
7WANG Chuanshang CHEN Xiaohong WANG Xiaofeng CHENG Long.Ontogeny of the Traumatocrinus hsui[J].Acta Geologica Sinica(English Edition),2011,85(3):544-548. 被引量：2
-
8Xiaoping Han,Hao Yu,Daosheng Huang,Yang Xu,Assieh Saadatpour,Xia Li,Lengmei Wang,Jie Yu,Luca Pinello,Shujing Lai,Mengmeng Jiang,Xueying Tian,Fen Zhang,Yanhong Cen,Yuko Fujiwara,Wei Zhu,Bin Zhou,Tianhua Zhou,Hongwei Ouyang,Jianan Wang,Guo-Cheng Yuan,Shumin Duan,Smart H Orkin,Guoji Guo.A molecular roadmap for induced multi-lineage transdifferentiation of fibroblasts by chemical combinations[J].Cell Research,2017,27(3):386-401. 被引量：2
-
9Qichao WANG,Xianmin ZHU,Yun FENG,Zhigang XUE,Guoping FAN.Single-cell genomics： An overview[J].Frontiers in Biology,2013,8(6):569-576.
-
10Raymond L. BERNOR,SUN Bo-Yang.Morphology through ontogeny of Chinese Proboscidipparion and Plesiohipparion and observations on their Eurasian and African relatives[J].古脊椎动物学报,2015,53(1):73-92. 被引量：3
