摘要
目的探讨单孔胸腔镜肺叶切除术和系统性淋巴结清扫手术治疗肺癌的临床效果。方法回顾性分析2010年1月至2015年2月在安徽省胸科医院行单孔胸腔镜肺叶切除术的35例肺癌患者(单孔组)和行三孔法胸腔镜手术的65例患者(三孔组)。比较两组患者手术时间、术中出血量、术后住院时间及费用、胸腔引流管放置时间及引流量、疼痛视觉模拟评分(VAS)、并发症发生情况等,观察两组患者术前和术后血清炎性因子C反应蛋白(CRP)、血清淀粉样蛋白A(SAA)水平变化。结果单孔组患者手术时间、术中出血量、术后住院时间和费用均低于三孔组患者,差异均无统计学意义(均P>0.05);两组患者术后CRP及SAA水平比较,差异有统计学意义(t=3.86,5.11,P<0.05);单孔组患者VAS评分[(6.5±2.1)分]低于三孔组[(8.1±4.7)分],差异有统计学意义(t=3.25,P<0.05);单孔组患者并发症发生率(8.6%)高于三孔组(7.7%),差异无统计学意义(P>0.05)。结论与三孔法比较,单孔法可有效治疗肺癌,减轻患者术后疼痛,降低患者术后急性期反应,提高患者术后生活质量。
Objective To observe the clinical effect of single utility port video-assisted thoracoscopic lung resection and system of lymphadenitis in patients with lung cancer. Methods One hundred cases lung cancer patients from January 2010 to February 2015 were collected. 35 cases（ single port group）were given single utility port video-assisted thoracoscopic surgery,while 65 cases（ three holes group） were understood three-port thoracoscopic surgery. The operative time,bleeding volume,postoperative hospitalization time and cost,pleural drainage tube placement time and drainage,VAS score,complications were observed. The CRP and SAA levels preoperative and postoperative were observed. Results There was no difference of operative time,bleeding volume,postoperative hospitalization time and cost between two groups（ P〈0. 05）. There was statistically significant of CRP and SAA level（ t = 3. 86,5. 11,P〈0. 05）; VAS scores of the single port group was lower than that of the three-port group [（ 6. 5 ± 2. 1） vs（ 8. 1 ± 4. 7） ]（ t = 3. 25,P〈0. 05）; The complication rate of single port group was higher than that of three-port group（ 8. 6% vs7. 7%,P〈0. 05）. Conclusion Compared with three-port surgery,single port surgery can be also effective in the treatment of lung cancer,reduce postoperative pain,reduce acute postoperative reaction,improve the quality of life of patients.
出处
《中国肿瘤临床与康复》
2016年第8期939-942,共4页
Chinese Journal of Clinical Oncology and Rehabilitation
