摘要
目的探讨氢氧化钙糊剂联合根管治疗术治疗牙髓炎或根尖炎的临床疗效。方法选取2014年12月～2015年8月杭州口腔医院确诊牙髓炎或根尖炎的患者76例,随机分成2组,每组38例。对照组治疗牙数65颗,行常规根管治疗术后,予氧化锌碘仿丁香油粘固粉充填根管;观察组治疗牙数71颗,行常规根管治疗术后,予氢氧化钙糊剂充填根管。观察并比较2组患者治疗前后牙周指数（periodontal index,PI）、根管治疗期间疼痛（inter-appointment emergenc,IAE）情况,血清炎症因子水平以及临床疗效。结果与治疗前比较,2组患者菌斑指数（plaque index,PLI）、探诊后出血指数（bleeding index,BI）、牙周袋探诊深度（periodontal depth,PD）以及牙龈指数（gingival index,GI）均降低（P〈0.05）,血清炎性因子IL-6、IL-8、IL-1β以及TNF-α水平亦均降低（P〈0.05）;与对照组比较,观察组PLI、BI、PD及GI均较低（P〈0.05）,血清炎性因子IL-6、IL-8、IL-1β以及TNF-α水平较低（P〈0.05）。2组IAE发生情况差异有统计学意义（P〈0.05）。实验组临床疗效率88.73%,显著高于对照组的72.31%（P〈0.05）。结论氢氧化钙糊剂联合根管治疗术可有效治疗牙髓炎或根尖炎,明显改善患牙的牙周情况,显著降低根管治疗期间疼痛的发生以及血清炎性因子水平。
Objective To investigate the clinical curative effect of calcium hydroxide paste combined with root canal in treatment of pulpitis and apicitis. Methods A total of 76 patients with pulpitis and apicitis from Dec. 2014 to Aug. 2015 were collected and randomly divided into two groups,38 cases in each group. Control group（ 65 tooth） were treated by routine root canal therapy,with zinc oxide iodoform clove oil cement filling root canal;experimental group（ 71 tooth） were treated by routine root canal therapy,with calcium hydroxide paste filling root canal. Periodontal index,pain during root canal therapy（ IAE）,serum inflammatory factors and clinical curative effect were observed and compared between two groups pre-and posttreatment. Results Compared with pre-treatment,periodontal index of PLI,BI,PD and GI in two groups were all lower（ P〈0. 05）,and IL-6,IL-8,IL-1β and TNF-αwere lower（ P〈0. 05）. Compared with control group,PLI,BI,PD and GI of experimental group were lower（ P〈0. 05）,IL-6,IL-8,IL-1β and TNF-α were lower（ P〈0. 05）,too. The difference of IAE incidence between two groups was significant（ P〈0. 01） and the clinical curative effect of experimental group was 88. 73%,higher than 72. 31% of control group（ P〈0. 05）. Conclusion Calcium hydroxide paste combine with root canal therapy in treatment of pulpitis and apicitis are effective,which can significantly improve periodontal condition of tooth,reduce the occurrence of pain during root canal therapy.
出处
《中国生化药物杂志》
CAS
2016年第6期79-81,共3页
Chinese Journal of Biochemical Pharmaceutics
关键词
牙髓炎
根尖炎
氢氧化钙
根管治疗术
pulpitis
apicitis
calcium hydroxide paste
root canal treatment
