摘要
目的探讨下肢动脉缺血性疾病的临床发病情况及治疗措施。方法回顾性分析血管外科2014年1月—2015年7月期间共收治228例下肢动脉缺血性疾病患者的临床资料,治疗上根据疾病缓急、病变部位及特点选择个体化治疗方案,包括药物治疗,股、腘动脉切开Fogarty球囊导管取栓术,股、腘动脉顺行置管溶栓术,病变段动脉球囊扩张或支架植入术,取自体大隐静脉或人工血管行动脉旁路移植术,截肢术,多种治疗手段相结合的复合式手术等。结果急性下肢动脉缺血患者共87例,急性下肢动脉栓塞患者48例,急性下肢动脉血栓形成患者39例,经治疗有效79例(90.8%),无效8例(9.2%),截肢7例(8.0%),死亡1例(1.2%);慢性下肢动脉缺血患者共141例,下肢动脉硬化闭塞症患者105例,下肢血栓闭塞性脉管炎患者36例,经治疗有效127例(90.1%),无效14例(9.9%),截肢12例(8.5%),死亡2例(1.4%)。结论下肢动脉缺血性疾病的发病率越来越高,若治疗不及时致残、致死率较高,治疗下肢缺血性疾病,为了降低致残、致死率,应根据疾病缓急、病变部位及特点结合患者自身状况综合考虑选择药物、腔内成形、开放手术或多种治疗手段相结合的治疗方式。
Objective To evaluate the clinical incidence and therapeutic measures of lower extremity arterial ischemic disease. Methods The clinical data of 228 patients with lower extremity arterial ischemic disease were retrospectively analyzed ,which included drug treatment, embolectomy, catheter directed thrombolysis（ CDT）, percutaneous transluminal angioplasty（ PTA）, artery bypass grafting, amputation and the combination of a variety of treatments who were admitted to our hospital from January,2014 to July,2015. Results There were 87 cases of acute arterial ischemia,48 cases of acute artery embolism,39 cases of acute arterial thrombosis,79 cases were effective （90.8%）, 8 cases were invalid （9.2%）, amputation in 7 （8.0%）, die in 1 （1.2%） ;in 141 cases of chronic ischemia, atherosclerosis occlusion（ASO） in 105 ca- ses, thromboangiitis obliterans （TAO） in 36 cases, effective in 127 cases （90.1% ） , invalid in 14 cases （9.9%）, amputa- tion in 12 （8.5 % ）, die in 2 （ 1.4% ）. Conclusion The increasing incidence of ischemic disease of lower extremity, if treatment is not timely, disability, lethal rate is higher, in order to reduce the morbidity and mortality rate, it should be according to the priorities of the disease, lesion location and the characteristic of combining the patients＇ conditions considering the choice of drugs, percutaneous transluminal angioplasty, open surgery or a combination of a variety of treatments.
出处
《中华全科医学》
2016年第10期1635-1637,1650,共4页
Chinese Journal of General Practice
基金
2016年度安徽高校自然科学研究项目(KJ2016-SD38)
关键词
动脉缺血
置管溶栓
动脉旁路移植
腔内成形
Arterial ischemia
Catheter-directed thrombolysis
Arterial bypass grafting
Percutaneous transluminal angioplasty
