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心肺复苏期间酸碱变化的特点及应用

Features and applications of acid-base changes in cardiopulmonary resuscitation
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摘要 随着心脑血管疾病的增加,心搏骤停的发生率不断升高。心肺复苏(CPR)是抢救心搏骤停患者必要的措施,但目前临床上复苏成功率依旧很低。体内酸碱失衡是影响复苏效果的重要原因之一。通过回顾国内外学者对CPR期间患者体内酸碱变化特点及机制进行的大量研究结果,发现CPR期间体内存在反常性高碳酸血症及二氧化碳(CO2)超射的现象,对临床工作具有指导意义。但有关CPR期间动脉血气变化及其变化过程的具体时间、治疗性高碳酸血症,以及不同病因、不同人群CPR期间酸碱变化是否存在差异的研究甚少,需要积累大量临床数据深入研究。 The cases of cardiac arrest are increasing because of the increased incidence of cardiovascular diseases. Cardiopulmonary resuscitation (CPR) is the necessary measure to rescue these patients. But the success rate of recovery is still low. Acid-base disturbance is one of the important factors affecting the recovery effect. Overseas and domestic studies in recent years focused on the acid-base changes and mechanism in CPR have founded that it exits extraordinary hypercapnia and CO2 spike, which have important guidance to the clinical work. The research for the arterial blood gas analysis during CPR, changes in the exact time, and treatment of hypercapnia and acid-basic change in different etiology and different populations were very few, therefore the a lot of clinical data is needed to accumulate for further study.
出处 《中华危重病急救医学》 CAS CSCD 北大核心 2016年第7期666-668,共3页 Chinese Critical Care Medicine
基金 国家自然科学基金面上项目(81171869) 四川省医药卫生科研项目(130316)
关键词 心肺复苏 血气分析 酸碱变化 Cardiopulmonary resuscitation Blood gas analysis Acid-base change
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