摘要
目的分析原发性高血压患者早餐餐后低血压(postprandial hypotension,PPH)与血压晨峰的相关性。方法将行24 h动态血压监测的原发性高血压患者135例分三组,其中仅有原发性高血压组(非PPH组)45例,合并早餐餐后低血压组45例,合并中晚餐餐后低血压组45例,观察三组平均血压、血压负荷值、勺型率、血压变异性及晨峰值等指标。结果 (1)合并早餐餐后低血压组24 h、日间、夜间收缩压变异性及24 h、日间舒张压变异性明显高于非PPH组及合并中晚餐餐后低血压组,且差异有统计学意义(P<0.05)。(2)合并早餐餐后低血压组患者血压晨峰值及晨峰发生率明显高于非PPH组及合并中晚餐餐后低血压组,差异有统计学意义(P<0.05)。(3)餐前血压越高越容易发生餐后低血压,餐前血压与餐后血压下降值成正相关(r=0.548,P<0.001),早餐餐前血压与早餐后血压下降值成正相关(r=0.623,P<0.001)。结论餐前血压越高越易发生餐后低血压,早餐餐后低血压患者血压变异性增高,更易发生晨峰现象。
Aim To analyse correlation between postprandial hypotension（ PPH） of breakfast and morning blood pressure surge in essential hypertension patients. Methods 135 patients with essential hypertension who proceed 24 h ambulatory blood pressure were divided into non-PPH group（ n = 45）,and postprandial hypotension of breakfast group（ PPH-1 group）（ n = 45）,and postprandial hypotension of lunch and dinner（ PPH-2 group）（ n = 45）. Average blood pressure,blood pressure load values,dipper rate,blood pressure variability and morning surge were observed in three groups. Results（ 1） 24 hS BPV,24 hD BPV,dS BPV,dD BPV,nS BPV of PPH-1 group was obviously higher than that of the non-PPH and PPH-2 group,and the difference was statistically significant（ P〈0.05）.（ 2） The morning surge value and morning blood pressure surge ratio of the PPH-1 group was significantly higher than that of non-PPH and PPH-2 group（ P〈0.05）.（ 3） Preprandial SBP was positively correlated with postprandial fall in SBP after meal（ r= 0.548,P〈0.001）.Breakfast preprandial SBP was positively correlated with postprandial fall in SBP after breakfast（ r = 0.623,P〈0.001）.Conclusion The higher the preprandial blood pressure,the more prone to PPH,breakfast postprandial hypotension patients have a higher blood pressure variability,morning surge phenomenon happens more easily.
出处
《中国动脉硬化杂志》
CAS
北大核心
2016年第7期693-697,共5页
Chinese Journal of Arteriosclerosis
关键词
餐后低血压
血压晨峰
血压变异性
Postprandial Hypotension
Morning Blood Pressure Surge
Blood Pressure Variability
