摘要
目的探讨鼻塞式持续正压通气(NCPAP)对小儿重症肺炎并发呼吸衰竭的治疗效果。方法将2012年11月到2015年10月来华中科技大学同济医学院附属孝感医院接受治疗的小儿重症肺炎并发呼吸衰竭患者82例,按照试验治疗方式的不同,将82例患儿随机分为试验组和对照组两组,每组41例。两组患儿在采用吸痰、平喘、抗生素等治疗的基础上,对照组采用面罩供氧方式,试验组采用鼻塞式持续正压通气供氧的治疗方式。比较两组患儿治疗总有效率、血气分析指标:血氧分压(Pa O2)、二氧化碳分压(Pa CO2)转变情况、两组患儿治疗前后主要临床症状缓解情况。结果 1试验组患儿的心率恢复正常时间、发绀消失时间、呼吸困难缓解时间、肺部啰音消失时间和临床症状体征消失时间,较对照组明显缩短(P<0.05);2试验组治疗有效率(92.68%,n=41)高于对照组的治疗有效率(75.61%,n=41),差异有统计学意义(χ2=4.48,P<0.05);3两组患儿在治疗前30 min血气分析指标比较无显著差异性(P>0.05),但治疗前后两组患儿的血气分析指标均得到明显改善(P<0.05),且试验组改善幅度优于对照组(P<0.05)。结论鼻塞式持续正压通气对小儿重症肺炎并发呼吸衰竭的治疗效果显著,快速缓解临床症状,改善血气分析指标,值得临床推广。
Objective To explore the application effect of nasal continuous positive airway pressure( NCPAP) for respiratory failure in children with severe pneumonia. Methods A total of 82 0. 5 ~ 3year- old children undergoing surgery for Severe Pneumonia merger of Respiratory Failure in our Hospital between November 2012 and October 2015 were randomly divided into experiment group and control group,with 41 in each group. Both groups received routine treatment including anti- infection therapy,sputum aspiration,and children of control group were given extra mask oxygen- inspiration,while children of treatment group were given extra NCPAP. The total effective rate,blood gas analysis and clinical symptoms of the children were compared between the two groups. Results 1 The total effective rate( 92. 68%,n = 41) of experimental group was significantly higher than that in the control group( 75. 61%,n = 41)( χ2= 4. 48,P < 0. 05); 2 The clinical symptoms and signs disappeared time of children in the experimental group were significantly shorter than the control group,such as heart rate to restore normal time, dyspnea remission time, pulmonary rales disappeared time and cyanosis disappeared time( P < 0. 05). 3 The blood gas analysis of 30 min before treatment was not significantly different( P > 0. 05),while the analysis index of the two groups were significantly improved( P < 0. 05)before and after the treatment,and the experimental group improvement rate was higher than that in control group( P < 0. 05). Conclusions Nasal continuous positive pressure ventilation was effective in the treatment of severe pneumonia complicated with respiratory failure in children. It can quickly relieve clinical symptoms and improve blood gas analysis index. It was worthy of clinical promotion.
出处
《广东微量元素科学》
CAS
2016年第6期47-51,共5页
Trace Elements Science
