摘要
目的用Meta分析方法研究脑卒中患者发生肺部感染危险因素。方法检索PubMed、EBSCO、Cochrane、中国知网及万方数据库中2010-01-2015-08有关脑卒中发生肺部感染危险因素的文献,对符合纳入标准的文献进行质量评价和数据提取后,采用Stata统计软件进行Meta分析。结果共纳入8篇文献,其中病例组606例,对照组3 104例,Meta分析结果显示：高龄（OR=3.19,95%CI=1.34-7.56）、糖尿病（OR=2.54,95%CI=1.64-3.92）、吸烟（OR=2.26,95%CI=1.24-4.12）、吞咽困难（OR=2.50,95%CI=1.08-5.77）、意识障碍（OR=2.47,95%CI=1.69-3.62）是脑卒中患者发生肺部感染的危险因素,而性别与脑卒中患者发生肺部感染无显著相关性（OR=2.06,95%CI=0.89-4.74）。结论该研究结果显示高龄、合并糖尿病、吸烟、吞咽困难及意识障碍的脑卒中患者容易发生肺部感染。
Objective To explore the risk factors of lung infection in patients withi stroke by using Meta-analysis. Methods The relevant papers were searched in PubMed,EBSCO,Cochrane,CNIKand Wanfang databases from Januam 2010 to August 2015. The papers were evaluated and the data were extracted. Stata software was used to analyze the data. Results Eight papers with 606 cases and 3 104 controls were included. The Meta-analysis showed that elder age,diabetes mellitus,smoking,dysphagia,disturbance of consciousness were the independent risk factors of lung infection in patients with stroke. Gender had no significant association with lung infection in patients withstroke. Conclusion Elder age,diabetes mellitus,smoking,dysphagia and disturbance of consciousness are the risk factors of lung infection in patients with stroke.
出处
《中国临床新医学》
2016年第6期481-484,共4页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
基金
国家自然科学基金项目(编号:81360191)
广西卫计委科研课题(编号:Z2015105)
