摘要
目的：观察复方苦参注射液联合化疗治疗晚期肺腺癌患者的疗效。方法：87例晚期肺腺癌患者随机分为复方苦参注射液联合化疗组（观察组）44例和单纯化疗组（对照组）43例。临床观察终点指标包括有效率、至病情进展时间和生活质量。结果：观察组总有效率36.4%,对照组总有效率30.2%,2组疗效差异无统计学意义（P〉0.05）;观察组至病情进展时间与对照组差异无统计学意义（P〉0.05）。观察组生活质量评分显著优于对照组（P〈0.01）。观察组不良反应发生率低于对照组（P〈0.05～P〈0.01）。结论：复方苦参注射液无法提高治疗反应和延长生存期,但能改善患者的生活质量,并能减轻化疗的不良反应。
Objective： To investigate the clinical efficacy of Fufangkushen injection combined with chemotherapy in the treatment of advanced lung adenocarcinoma. Methods： Eighty-seven patients with advanced lung adenocarcinoma were randomly divided into the Fufangkushen injection combined with chemotherapy group（ observation group,44 cases） and chemotherapy alone group（ control group,43 cases）. The effective rate,progression-free survival and quality of life in two groups were observed. Results： The total effective rates in observation group and control group were 36. 4% and 30. 2%,respectively,the difference of which was not statistically significant（ P〈0. 05）. The difference of the progression-free survival between two groups was not statistically significant（ P〈0. 05）. The score of quality of life in observation group was better than that in control group（ P〈0. 01）. The incidence of adverse reaction in observation group was lower than that in control group（ P〈0. 05 to P〈0. 01）. Conclusions： Fufangkushen injection combined with chemotherapy treatment can not improve treatment response and prolong survival time,but which can improve the quality of life and alleviate the adverse reaction of chemotherapy.
出处
《蚌埠医学院学报》
CAS
2016年第3期320-322,共3页
Journal of Bengbu Medical College
关键词
肺肿瘤
复方苦参注射液
吉西他滨
顺铂
lung neoplasms
Fufangkushen injection
gemcitabine
cisplatin
