摘要
目的：观察雾化吸入用布地奈德混悬液治疗小儿急性感染性喉炎的临床效果。方法选取76例急性感染性喉炎患儿，采用随机数字表法分为观察组（n＝38）及对照组（n＝38），两组患儿均接受常规治疗，在此基础上对照组患儿采用地塞米松雾化吸入治疗，观察组患儿采用雾化吸入用布地奈德混悬液治疗，评估两组患儿临床治疗效果。结果观察组临床治疗总有效率97．37％，显著高于对照组的76．32％，差异有统计学意义（χ2＝19．392，P＜0．05）；观察组咳嗽、声嘶、发热、呼吸困难、喉鸣音等症状消失时间分别为（2．21±1．12）d、（2．21±0．54）d、（1．21±0．33）d、（1．61±0．81）d、（1．23±0．21）d，均显著短于对照组（t＝4．118、4．362、6．369、3．943、3．946，均P＜0．05）；两组未出现明显不良反应，观察组患儿病程持续时间、住院时间分别为（2．11±0．72）d、（3．09±0．54）d，显著短于对照组（t＝4．966、5．795，均P＜0．05）；观察组满意度为（91．23±4．52）％，显著高于对照组，差异有统计学意义（χ2＝4．203，P＜0．05）。结论布地奈德混悬液雾化吸入治疗小儿急性感染性喉炎可明显改善临床症状，无不良反应，缩短病程和住院时间，提高临床治疗效果，值得临床推广应用。
Objective To observe and analyze the clinical effect of aerosol inhalation with budesonide suspension liquid drug in the treatment of children with acute infectious laryngitis.Methods 76 children with acute infectious laryngitis were divided into the observation group （n=38） and control group （n=38）.Two groups of chil-dren were treated with conventional therapy,on the basis of conventional therapy,the control group was given dexam-ethasone aerosol inhalation,the observation group was treated with atomization of inhalation with budesonide suspen-sion liquid.The clinical therapeutic effects of the two groups were assessed.Results The total effective rate of the observation group was 97.37%,which was significantly higher than 76.32% of the control group,the difference was statistically significant （χ2 =19.392,P〈0.05）.The disappeared time of fever,cough,hoarseness,dyspnea,throat beep symptoms in the observation group was （2.21 ±1.12）days,（2.21 ±0.54）days,（1.21 ±0.33）days,（1.61 ± 0.81）days,（1.23 ±0.21）days,which were significantly shorter than the control group,the differences were statisti-cally significant （t=4.118,4.362,6.369,3.943,3.946,all P〈0.05）.The two groups had no obvious adverse reac-tion,The duration and hospitalization time of the observation group were （2.11 ±0.72）days,（3.09 ±0.54）days respectively,which were significantly shorter than the control group （t=4.966,5.795,all P〈0.05）.The satisfaction rate of the observation group was （91.23 ±4.52）%,which was significantly higher than the control group,the differ-ence was statistically significant （χ2 =4.203,P〈0.05）.Conclusion For the children with acute infectious laryngi-tis,inhalation with budesonide suspension liquid therapy can significantly improve clinical symptoms,with no adverse reaction,shorten the course of disease and hospitalization time,reduce the physical and psychological suffering of chil-dren,improve the clinical treatment effect,promote the healthy growth of children,it is worthy of clinical application.
出处
《中国基层医药》
CAS
2016年第8期1232-1235,共4页
Chinese Journal of Primary Medicine and Pharmacy
关键词
小儿
急性感染性喉炎
吸入用布地奈德混悬液
雾化
吸入
疗效
Children
Acute infectious laryngitis
Inhalation of budesonide
Atomization
Inhalation
Curative effect
