摘要
目的：探讨乳酸菌阴道胶囊对妊娠晚期合并细菌性阴道病（BV）患者不良妊娠结局的预防作用。方法：将94例妊娠晚期合并BV患者,根据就诊的门诊号顺序将其分为联合组48例和对照组46例。联合组患者予以乳酸菌阴道胶囊和甲硝唑栓联合治疗,对照组予以单纯的甲硝唑栓治疗。观察两组治疗7d后的临床疗效,并比较其不良妊娠结局。结果：治疗7d后,在临床总有效率方面联合组患者（95.83%）明显高于对照组（80.43%）（χ^2=5.39,P〈0.05）;联合组患者在早产、胎膜早破和新生儿黄疸等不良妊娠结局发生率明显低于对照组（P〈0.05）。两组在产褥感染、低体重儿等不良妊娠结局发生率方面比较差异无统计学意义（P〉0.05）。结论：乳酸菌阴道胶囊辅助治疗妊娠晚期合并BV患者的疗效较确切,对其不良妊娠结局具有良好的预防作用,可减少其早产、胎膜早破和新生儿黄疸发生率。
Objectives： To discuss the prevention effect of lactobacillus vagina capsules on adverse pregnancy outcomes of patients with bacterial vaginosis（ BV） in late pregnancy. Methods： 94 patients with BV in late pregnancy were divided into combined group（ 48 cases） and control group（ 46 cases） in accordance with sequential treatment number of outpatient service. The patients in combined group were given lactobacillus vagina capsules and metronidazole tablets,while the patients in control group were only given metronidazole tablets. The clinical curative effects in two groups were observed after 7 days＇ medical treatment,and the adverse pregnancy outcomes were compared as well. Results： After 7 days＇ medical treatment,total clinical efficiency of patients in combined group（ 95. 83%） was much higher than that in control group（ 80. 43%）（ χ^2= 5. 39,P〈0. 05）. The occurrence rates of premature birth,premature rupture of fetal membranes,jaundice of newborn and other adverse pregnancy outcomes of patients in combined group were much lower than those in control group（ P〈0. 05）. After comparing the occurrence rates of puerperal infection,infant of low- birth weight and other adverse pregnancy outcomes,no statistical differences was found（ P〉0. 05）. Conclusions： Lactobacillus vagina capsules has reliable curative effect in the treatment of patients with BV in late pregnancy as adjunctive therapy（ AT）,which has favorable prevention effect on adverse pregnancy outcomes and can reduce the occurrence rates of premature birth,premature rupture of fetal membranes and jaundice of newborn.
出处
《中国性科学》
2016年第3期127-129,共3页
Chinese Journal of Human Sexuality
关键词
细菌性阴道病
妊娠晚期
乳酸菌阴道胶囊
妊娠结局
Bacterial vaginosis（BV）
Late pregnancy
Lactobacillus vagina capsules
Pregnancy out comes
