摘要
目的观察右美托咪定术前滴鼻用于腹股沟疝手术小儿的镇静及预防术后躁动的临床效果。方法择期腹股沟疝手术患儿40例,年龄1~5岁,ASA分级Ⅰ级,随机均分为两组,术前30min分别经鼻腔给予右美托咪定1μg/kg（Dex组）和等容量生理盐水（NS组）,给药30min后评估患儿的镇静评分、与父母分离时的情绪评分、面罩吸入诱导抵抗评分;观察并记录术后30min、1h、2h的躁动评分。结果 Dex组的镇静评分、与父母分离时的情绪评分、面罩吸入诱导抵抗评分均优于NS组,术后各时间段的躁动评分均低于NS组（P〈0.05）。结论右美托咪定术前滴鼻可安全用于小儿腹股沟疝手术,可产生良好的镇静作用,同时减少术后躁动的发生。
Objective To observe the clinical effect of preoperative intranasal dexmedetomidine on sedation and preventing postoperative agitation in children inguinal hernia operation.Methods Forty children patients,aged 1-s5 years old,ASA Ⅰ,were selected and equally randomized into 2groups,receiving intranasally dexmedetomidine 1μg/kg（group Dex）and the same volume of normal saline（group NS）at preoperative 30 min respectively.The sedation score,emotion score when separating from their parents,mask inhalation induction resistance score were evaluated at 30 min after medication,furthermore the agitation scores were observed and recorded at postoperative 30 min,1,2h.Results The sedation score,emotion score when separating from their parents and mask inhalation induction resistance score in the Dex group were superior to the NS group,moreover the agitation score at each points were lower than those in the NS group（P〈0.05）.Conclusion Preoperative intranasal dexmedetomidine can be safely used in children inguinal hernia operation,has better sedative effect,meanwhile reduces the postoperative agitation occurrence.
出处
《重庆医学》
CAS
北大核心
2016年第8期1034-1036,共3页
Chongqing medicine
基金
国家自然科学基金资助项目(81371242)
关键词
右美托咪定
术前用药
滴鼻
儿童
dexmedetomidine
premedication
intranasal
children
