摘要
目的通过分析42例腺样囊性癌的临床病例资料，旨在探讨腺样囊性癌的临床发病特点及预后影响因素。方法选取2000年6月～2010年5月在我院口腔科手术治疗并经病理科确诊为涎腺腺样囊性癌（salivaryadenoidcysticcarcinoma，SACC）患者42例，按照国际抗癌联盟2002年TNM临床分类方法，对其进行临床分类，按照世界卫生组织2005年涎腺肿瘤组织学分类方法进行病理分类。结果腺样囊性癌多发于腮腺及颌下腺．平均年龄51岁，男女比例4：3，发生于腭部及小涎腺的SACC复发率和转移率高于腮腺。临床3期和4期较1期和2期复发率高。病理实性型较病理腺样一管状型复发率和转移率高。神经侵犯者较非神经侵犯者复发率和转移率高。结论SACC是涎腺肿瘤中常见的恶性肿瘤之一，SACC术后转移率和复发率较高，与肿瘤的发病部位、临床TNM分期、病理学分型及有无神经侵犯有相关性。
Objective To discuss the clinical features and influence factors of prognosis in salivary adenoid cystic carcinoma （SACC） by analysis on the clinical material of 42 SACC cases. Methods 42 confirmed SACC patients receiving operation in our hospital from June 2000 to May 2010 were selected and clinical classification was made based on 2002 TNM clinical classification method by International Union Against Cancer, while pathological classification was made by WHO 2005 histologic classification method of salivary neoplasm. Results Adenoid cystic carcinoma was commonly observed in parotid glands and salivary glands, with an average patients age of 51 years old and male female ratio of 4：3. The recurrence rate and metastasis rate of SACC in palatine and minor salivary glands were higher than those in parotid glands and submandibular glands. The recurrence rate was higher in SACC at III and IV clinical stage than at I and II clinical stage. The recurrence rate and metastasis rate were higher in solid tumors than in adenoid tubular tumors, and were also higher in patients with nerve invasion than in those without nerve invasion. Conclusion SACC is a common type of malignant neoplasm in salivary gland tumors. The recurrence rate and metastasis rate of SACC are relatively high, which depends on the pathogenic site, clinical TNM stage, pathogenic type, and having or not nerve invasion.
出处
《中国现代医生》
2016年第4期55-57,共3页
China Modern Doctor
关键词
涎腺肿瘤
腺样囊性癌
复发
转移
Salivary gland malignant tumor
Adenoid cystic carcinoma
Recurrence
Metastasis
