摘要
心搏骤停（cardiac arrest,CA）是指心脏机械功能（搏血功能）突然停止,并伴自主呼吸消失和意识丧失的临床急症。针对CA的救治措施称为心肺脑复苏（cardio-pulmonary-cerebral resuscitation,CPCR）。如果抢救不及时,最终导致猝死（sudden death）。在抢救CA过程中,患者自主循环恢复（return of spontaneous circulation,ROSC）只是初级目标,CPCR的终极目标是良好的器官功能,尤其是良好的神经系统功能结局。
Cardiac arrest（CA）is a common cause of death,patients discharged from hospital usually have neurological deficit.Translational medicine research of CA is important for the improvement the results of patients with post-CA syndrome.Animal models of CA include asphyxial CA model,ventricular fibrillation CA model,potassium chloride induced CA model and exsanguination CA model.We reviewed the histories and methods of each model,and tried to make a simple assessment in this article.
出处
《临床急诊杂志》
CAS
2016年第1期4-8,共5页
Journal of Clinical Emergency
基金
中央高校基本科研业务费专项资金(No:2042014kf0271)
武汉市科技计划项目(No:2015060101010045)
关键词
心搏骤停
心肺复苏
窒息
心室纤颤
氯化钾
失血
cardiac arrest
cardio-pulmonary resuscitation
asphyxia
ventricular fibrillation
potassium chloride
exsanguination
