摘要
目的通过对本院备血患者不规则抗体筛查,发现有意义的不规则抗体,并分析其分布规律及临床意义。方法应用微柱凝胶法及盐水法对2014年4月-2015年3月10 512例备血患者标本进行抗体的筛选及鉴定。结果10 512例患者标本中检出不规则抗体55例(阳性率0.52%)。Rh系统共有21例(38.2%):抗-D 3例,抗-E11例,抗-c1例,抗-c E 6例;MNSs系统13例,均为抗-M;lewis系统共有6例,均为Lea;自身抗体9例;自身抗体合并抗-M1例;抗体特异性未确定有5例。结论建议将Rh E和Rh D血型抗原一起纳入常规血型检测,可尝试在因慢性疾病需长期输血患者中采用Rh E抗原同型输注。
Objective To investigate clinically irregular antibodies by screening the irregular antibodies in patients prepared for blood transfusion,and to analyze the pattern of distribution and clinical significance. Methods Micro-column gel and saline methods were used to screen and identify the irregular antibodies of 10 512 patients between April 2014 and March2015. Results Among 10 512 patient cases,55 cases had positive results in irregular antibody detection at a rate of 0.52%. 21 cases belonged to the Rh blood group system,including 3 cases of anti-D,11 cases of anti-E,1 case of anti-c and6 cases of anti-c E. 13 cases were anti-M,belonging to MN blood group system. Six cases were anti-Lea,belonging to Lewis blood group system. Nine cases were autoantibodies,in addition to one case of autoantibodies combined with anti-M antibodies. However,the specificity of antibodies in five cases was not determined. Conclusion Rh D and Rh E blood group antigens should be detected in routine blood grouping. Rh E antigen should be infused in chronic patients in need of long term transfusion.
出处
《中国输血杂志》
CAS
北大核心
2015年第12期1513-1515,共3页
Chinese Journal of Blood Transfusion
关键词
不规则抗体
抗体筛检
输血
irregular antibody
antibody screening
blood transfusion
