摘要
目的探讨不同胰岛素给药方法对治疗糖尿病的临床效果。方法从该院2013年7月—2014年7月住院治疗的糖尿病患者中筛选出92例作为研究对象,根据患者不同的胰岛素给药方式,将该92例患者分为对照组和观察组。观察组46例患者采用胰岛素泵连续皮下注射,对照组46例患者采用采用胰岛素分次常规皮下注射,对比分析两组患者的空腹血糖值、血糖达标时间、胰岛素用量及低血糖发生率等指标。结果两组患者组内比较,胰岛素输注后空腹血糖值明显低于输注前(P<0.01);两组患者组间比较,胰岛素输注前后空腹血糖值相比,差异无统计学意义(P>0.05)。观察组患者的血糖达标时间、胰岛素用量和低血糖发生率,明显低于对照组(P<0.05)。结论采用泵皮下连续注射胰岛素的给药方式,在降低血糖发生率和血糖达标时间及减少胰岛素用量等方面,效果明显优于分次皮下注射胰岛素,是一种安全方便、操作简单的胰岛素给药方式。
Objective To investigate the clinical effect of different insulin delivery methods in the treatment of diabetes mellitus. Methods 92 patients with diabetes mellitus underwent hospitalization in our hospital from July 2013 to July 2014 were selected as the subjects and divided into observation group and control group, 46 cases in each group according to the different insulin delivery methods. The patients in observation group were treated with continuous subcutaneous insulin infusion by insulin pump, while those in control group were treated with conventional fractionated subcutaneous injection of insulin. The fasting blood glucose, the time to achieve glycemic control, insulin dosage and the incidence of hypoglycemia were compared between the two groups. Results The fasting blood glucose levels after insulin infusion in the two groups were significantly lower than those before insulin infusion （P〈0.01）; and no significant difference in fasting blood glucose levels was found between the two groups before and after insulin infusion （P〉0.05）. The observation group had much shorter time for achieving glycemic control, less insulin dosage and lower incidence of hypoglycemia than the control group （P〈0.05）. Conclusion Continuous subcutaneous insulin infusion by insulin pump is a simple, safe and convenient way of giving insulin, it is much better than fractionated subcutaneous injection of insulin in the aspects of reducing the incidence of hypoglycemia and amount of insulin.
出处
《糖尿病新世界》
2015年第22期13-15,共3页
Diabetes New World Magazine
关键词
胰岛素泵
糖尿病
血糖
分次注射
Insulin pump
Diabetes
Blood glucose
Fractionated injection
