摘要
目的分析极低出生体质量儿（LBWI）医院感染的临床特点和危险因素。方法对2010年9月至2014年8月首都医科大学附属北京妇产医院新生儿重症监护病房（NICU）收治的431例LBWI的临床资料进行回顾性调查分析，统计其医院感染发生部位、病原菌分布及危险因素。结果LBWI的医院感染率为16．0％（69／431），共发生71例次，住院日相关的医院感染发生率11．4例次／1000住院日。感染部位以血液为主，占67．6％（48／71），其次为呼吸道，占21．1％（15／71）；共检出病原菌64株，以革兰阴性菌为主，其中肺炎克雷伯菌占32．8％（21／64）。胎龄〈32周、经外周中心静脉置管是LBWI发生医院感染的危险因素（x2=7．486、22．489，P〈0．01）。结论LBWI是医院感染发生的高危人群，其中胎龄〈32周、经外周中心静脉置管等是发生医院感染的危险因素。
Objective To study the clinical features and risk factors of nosoeomial infection in low birth weight infant （LBWI）. Methods A retrospectively analysis of 431 LBWIs in neonatal intensive care unit from September 2010 to August 2014 was preformed. The infection site and infection pathogen were recorded; the risk factors were analyzed. Results There were 69 infants with nosoeomial infection, with incidence of 16. 0% （69/431）, and incidence of 11.4 cases per 1 000 patient hospitalization. The main infection site was blood infections C67.6% （48/71） ], followed by respiratory tract infections [21.1% （ 15/71 ） ] ; the main bacteria was gram-negative bacteria, in which Klebsiella pneumonia accounted for 32. 8% （21/64）. Gestational age less than 32 weeks, by peripheral central venous tube was LBWI occurred hospital infection risk factors （X2 = 7. 486, 22. 489, P 〈 0. 01 ）. Conclusions Incidence of nosoeomial infection in LBWI is higher than that of others. The risk factors include small gestational age, peripherally inserted central catheter, and so on.
出处
《中国医药》
2016年第2期264-267,共4页
China Medicine
关键词
极低出生体重儿
医院感染
危险因素
Low birth weight infant
Nosoeomial infection
Risk factors
