摘要
目的探讨老年糖尿病患者多药耐药菌感染状况,为临床防治提供指导依据。方法选取2012年1月-2015年6月住院治疗的老年糖尿病医院感染患者248例为研究对象,分析老年糖尿病患者的医院感染率、科室分布、基础疾病分布、感染部位及病原菌分布;采用SPSS 17.0软件对数据进行统计分析。结果老年糖尿病患者感染率与多药耐药菌感染率均呈现逐年上升的趋势,医院同期非糖尿病患者医院感染率为0.8%,显著低于糖尿病患者的2.0%,差异有统计学意义(P<0.05);老年糖尿病患者多药耐药菌感染科室分布以ICU、神经外科和神经内科为主,分别占36.0%、17.4%和14.0%;基础疾病以呼吸道疾病、心血管疾病和脑卒中为主,分别占33.7%、19.8%和16.3%;感染部位以呼吸系统、泌尿系统和皮肤为主,分别占64.0%、26.7%和20.9%;多处感染患者占19.8%;分离出病原菌197株,其中革兰阴性菌115株占58.4%,革兰阳性菌64株占32.5%,真菌18株占9.1%。结论老年糖尿病患者多药耐药菌感染非常严重,以ICU最为多发,感染部位以呼吸道感染为主,应对感染高发人群及时采取有效措施,预防多药耐药菌感染的发生。
OBJECTIVE To explore the prevalence of multidrug-resistant organisms（MDROs）infections in the elderly patients with diabetic mellitus so as to provide guidance for clinical prevention and treatment.METHODS A total of 248 elderly diabetic mellitus patients with nosocomial infections who were hospitalized from Jan 2012 to Jun2015were recruited as the study objects,then the incidence of nosocomial infections,distribution of departments,distribution of underlying diseases,infection sites,and distribution of pathogens were observed,and the statistical analysis of data was performed with the use of SPSS 17.0software.RESULTS Both the infection rate and the incidence of MDROs infections were increased year by year in the elderly patients with diabetic mellitus;the incidence of nosocomial infections was 0.8%in the elderly patients without diabetic mellitus during the same period,significantly lower than 2.0%in the elderly patients with diabetic mellitus（P〈0.05）.Of the elderly diabetic mellitus patients with MDROs infections,36.0% distributed in the ICU,17.4%in the department of neurosurgery,14.0%in the department of neurology.Of the elderly patients with underlying diseases,33.7% had respiratory tract diseases,19.8% had cardiovascular diseases,and 16.3% had stroke.Of the elderly patients with the infections,64.0% had respiratory system infections,26.7% had urinary system infections,and 20.9% had skin infections;the elderly patients with multiple sites of infections accounted for 19.8%.Totally 197 strains of pathogens were isolated,including 115（58.4%）strains of gram-negative bacteria,64（32.5%）strains of gram-positive bacteria,and18（9.1%）strains of fungi.CONCLUSIONThe elderly patients with diabetic mellitus have very severe MDROs infections,which are the most prevalent in the ICU.The respiratory tract is dominant among the infection sites.It is necessary to take effective measures for the population at high risk of the infections so as to prevent the MDROs infections.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2016年第1期62-64,共3页
Chinese Journal of Nosocomiology
基金
新疆维吾尔自治区自然科学基金资助项目(2011211A054)
关键词
老年患者
糖尿病
多药耐药菌
感染
Elderly patient
Diabetic mellitus
Multidrug-resistant organism
Infection
