Sensory Disturbance as a Characteristic Symptoms of Methylmercury Poisoning in Niigata, Japan
Sensory Disturbance as a Characteristic Symptoms of Methylmercury Poisoning in Niigata, Japan
摘要
Fifty years have passed from the first official recognition of the methylmercury （MeHg） poisoning in Niigata （so called the second Minamata disease）, Japan in 2015. The first case of MeHg poisoning was found in January 1965, when two surveys were carried out for 20,000 inhabitants lived within 15 km from the mouth of the Agano river. From these surveys, 26 cases （including 5 cases of death） were officially recognized as MeHg poisoning. Moreover, 9 cases who had no symptoms but whose hair mercury concentration were over 200 ppm were found. Within 20 cases, 15 cases are among 26 cases officially recognized as having MeHg poisoning and 5 cases are among 9 cases who had no symptoms but whose hair mercury concentration were over 200 ppm in 1965. The distal dominant sensory disturbances of the extremities lasted for more than several decades among 20 cases. The sensory disturbance of the bilateral distal extremities could be used as the gold standard for the diagnosis of MeHg poisoning in the exposed areas. The distal dominant sensory disturbance of the extremities is a typical characteristic and important sign of the MeHg poisoning.
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