摘要
目的观察和分析解脲脲支原体(Uu)、沙眼衣原体(Ct)与胎膜早破(PROM)的关系及其对妊娠结局的影响,为临床预防及治疗提供参考依据。方法选取2013年1月-2014年12月180例患者为研究对象,根据Uu、Ct检测结果,将PROM孕妇分为感染组85例和非感染组35例,对两组不良妊娠结局的发生进行调查和比较,数据采用SPSS 13.0进行统计分析。结果早产PROM孕妇的Uu、Ct阳性率均显著高于足月PROM孕妇或正常分娩孕妇(P<0.05),感染组的早产、低出生体重儿、绒膜羊膜炎、新生儿肺炎的发生率显著高于非感染组(P<0.05),logistic多因素分析显示,PROM合并出现不良妊娠结局与Uu检测阳性、Ct检测阳性、孕周均具有相关性(P<0.05)。结论 PROM孕妇表现为Uu感染和Ct感染的升高,特别早产PROM孕妇的感染率较高,Uu感染和Ct感染及孕期较短均为PROM出现不良妊娠结局的独立危险因素,临床医师应给予高度重视并及时采取有效的干预措施,以改善母婴的预后。
OBJECTIVE To observe and analyze the relationship between Ureaplasma urealyticum （Uu）, Chlamydia trachomatis （Ct） infections and premature rupture of membranes （PROM） and its effects on the preg- nancy outcome so as to provide the basis for clinical prevention and treatment. METHODS Totally 180 cases of pregnant women with PROM admitted in the hospital from Jan. 2014 to Dec. 2013 were selected as the research objects. According to the detection results of Uu and Ct, the pregnant women with PROM were divided into the infection group （85 cases） and the non infection＇ group （35 cases）. The adverse pregnancy outcomes of the two groups were observed and compared. SPSS13.0 was employed to analyze the data statistically. RESULTS The pos- itive rates of Uu and Ct in the pregnant women with preterm PROM were significantly higher than those in the pregnant women with full-term PROM or the aormally delivery pregnant women （P〈0.05）. The incidences of the adverse pregnancy outcomes of premature, low birth weight, chorioamnionitis, neonatal pneumonia in the in- fection group were significantly higher than those in the non infection group （P〈0.05）. Logistic multivariate re- gression analysis showed that the incidence of PROM complicated with adverse pregnancy outcomes was correlated with the positive detection of Uu, the positive detection of Ct, and the pregnant period （P〈0.05）. CONCLUSION The infection rates of Uu and Ct in the pregnant women with PROM would increase, especially the rate of preg- nant women with preterm PROM is higher. Uu and Ct infection as well as shorter pregnant periods are the inde- pendent risk factors of adverse pregnancy outcomes. The clinicians should pay more attention and take timely, ef- fective intervention measures to improve the prognosis of the pregnant women and the newborns.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2015年第23期5491-5493,共3页
Chinese Journal of Nosocomiology
基金
浙江省科技厅基金资助项目(08001293)
关键词
胎膜早破
解脲脲支原体
沙眼衣原体
妊娠结局
Premature rupture of membranes
Ureaplasma urealyticum
Chlamydia trachomatis
Pregnancy out-come
