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单双侧入路经皮椎体成形术治疗骨质疏松性椎体压缩骨折的疗效比较 被引量:12

Comparison of the clinical effects by unilateral or bilateral percutaneous vertebroplasty for osteoporotic vertebral compression fracture
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摘要 目的:对比经皮椎体成形术(PVP)治疗骨质疏松性椎体压缩骨折(OVCFs)单双侧两种入路的临床疗效。方法:回顾性分析自2012年9月~2014年12月经皖南医学院弋矶山医院脊柱骨科诊治的骨质疏松性椎体压缩骨折患者,按手术入路不同分为单、双侧两组。评价指标:骨水泥量、骨水泥渗漏率、VAS评分、伤椎体高度变化及后凸畸形Cobb角纠正程度。结果:所有患者均顺利完成手术,疼痛得到不同程度缓解、伤椎体高度有明显恢复,Cobb角得到一定纠正,与术前比较差异有统计学意义(P〈0.01)。两组骨水泥注射量比较差异有统计学意义(P〈0.01),VAS评分、伤椎体高度恢复、Cobb角纠正度比较差异无统计学意义(P〉0.05)。单侧组骨水泥渗漏率明显比双侧组高,差异有统计学意义(P〈0.05)。结论:经皮椎体成形术单双侧入路均能恢复伤椎体高度,纠正后凸畸形并缓解疼痛。单侧入路骨水泥用量少,但骨水泥渗漏率明显较高。 Objective: To compare the clinical effects by unilateral or bilateral percutaneous vertebroplasty( PVP) for osteoporotic vertebral compression fractures( OVCFs). Methods: The patients with OVCF received treatment in our department between September 2012 and December 2014 were allocated to two groups by unilateral( n = 40) or bilateral( n = 31) procedures. Indicators,including consumption of the bone cement and its leakage,scoring on VAS,changes of the height of vertebral body and corrected Cobb angle before and after operation,were evaluated in two groups. Results: Operation was successful in all patients,who had pain relief to a certain degree as well as significant restoration of the vertebral height and Cobb angle after operation. The difference was significant( P〈0. 01). Although the consumption of the bone cement was different in the two groups( P〈0. 01),yet the difference was not significant regarding the VAS scores,recovery of the affected vertebral height and Cobb angle( P〉0. 05). Patients treated with unilateral approach had higher cement leakage than those treated with bilateral technique( P〈0. 05). Conclusion: Both unilateral and bilateral PVP may improves symptoms of OVCFs and result in significant restoration of the vertebral height and kyphosis correction. Although unilateral approach requires less dose of bone cement,yet it has higher incidence of cement leakage.
出处 《皖南医学院学报》 CAS 2015年第6期533-537,共5页 Journal of Wannan Medical College
基金 国家自然科学基金项目(81272048) 安徽省自然科学基金项目(1308085MHl52)
关键词 骨质疏松症 压缩骨折 单侧入路 双侧入路 椎体成形术 osteoporosis compression fracture unilateral approach bilateral approach vertebroplasty
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