摘要
目的 :研制治疗慢性前列腺炎的栓剂并考察其临床疗效。方法 :以苦豆子总生物碱 (TASa)为主药 ,用酸性染料分光光度法测定TASa的含量 ,并与前列安栓进行对照 ,观察其临床疗效。结果 :TASa的线性范围为0 14～15 4μg/ml,氧化苦参碱对照品的加样回收率为101 2 % ,RSD=0 55 %。结论 :该制剂制备工艺简单 ,质控方法可靠 ;对直肠刺激性小 ,临床疗效确切 ,值得临床推广应用。
OBJECTIVE:To prepare Sophora alopecurodies suppository for treating prostatitis chronica and observe its clinical therapeutic effect METHODS:The content of the total alkaloid in the suppository was determined with acid dye spectrophotometry and the therapeutic effect was observed in comparison with qianliean suppository RESULTS:The linear range of TASa was 0 14～15 4μg/ml,standard oxymatriner's recovery was 101 2%,RSD=0 55% CONCLUSION:This suppository is simple in preparation,reliable in quality-control It is slight in irritation to rectum and effective in clinical use The preparation is worth popularizing in clinical practice
出处
《中国药房》
CAS
CSCD
2002年第8期468-469,共2页
China Pharmacy
基金
甘肃省科技厅资助项目 (QS002-C33-010)
