摘要
目的观察非体外循环下冠状动脉旁路移植术(CABG)治疗冠心病的疗效。方法 170例冠心病患者随机分为体外循环下CABG组(On-pump组,n=85例)和非体外循环不停跳CABG组(Off-pump组,n=85例)。观察两组患者氧合指数(OI)、肺泡-动脉氧差(Aa DO2)、呼吸机辅助时间、正性肌力药物使用量及时间、术后24 h出血量、输血量及心肌酶值。结果 Off-pump组在出血量、输血量、辅助呼吸时间、呼吸指标均明显优于On-pump组,正性肌力药物使用时间及心肌酶值显著少于On-pump组(P<0.05,P<0.01)。结论采用非体外循环进行CABG治疗冠心病优于体外循环。
AIM To evaluate the effects of off-pump coronary artery bypass graft （CABG） surgery in treatment of coronary atherosclerotic heart disease. METHODS One hundred and seventy patients with coronary atherosclerotic heart disease were randomly divided into on-pump CABG group （on-pump group, n = 85 cases） and off-pump CABG group （ off-pump group, n = 85 cases）. The transfused blood volume, postoperative chest drain loss, oxygenation index （OI）, alveolar-arterial oxygen gradient （AaDO2 ）, ino- tropic support, myocardial enzyme, extubation time and length of stay in ICU were observed. RESULTS In the off-pump group, postoperative bleeding and transfusion were reduced significantly, AsDO2 and OI were better and the length of inotropic drug support, myocardial enzyme changes and complications were less than those in the on-pump group. Extubation time and length of stay in ICU were shorter in off-pump group. CONCLUSION Off-pump CABG attenuates myocardial and lung injuries, reduces blood transfusion, lowers complication rates and relieves patient pain. Thus, it is worth clinical promotion.
出处
《心脏杂志》
CAS
2015年第6期673-675,共3页
Chinese Heart Journal
