摘要
目的:观测受力方向对兔直肠黏膜位移量的影响。方法:通过测算直肠黏膜内脱垂(IRP)兔直肠黏膜层与黏膜下层的力学指标建立IRP兔肛门直肠有限元模型,模拟在直肠黏膜上施加大小相同方向不同的两种力(一种力垂直向下,一种力平行于直肠黏膜方向),以黏膜脱垂相对明显层面的不同节点为观测对象,计算两种力作用下的节点位移量。结果:测得兔直肠黏膜与黏膜下层的杨氏弹性模量为(4.088 8±0.161 5)MPa、泊松比为0.470 0±0.005 0、剪切弹性模量为(1.390 9±0.059 5)MPa。将数据输入兔肛门直肠有限元模型后,测算得两种力在兔直肠腹侧848与850节点的黏膜位移量无显著性差异(P>0.1),但在直肠中间位852节点、背侧的854与856节点存在显著性差异(P<0.05)。结论:受力方向影响兔直肠黏膜位移量,提示黏膜受力方向的差异可能影响排便。
Objective To observe the influence of different forced directions on the displacement of rabbit＇s rectal mucosa. Methods The finite element model of internal rectal prolapse （IRP） rabbit＇s anorectum was established by measuring the mechanics index of the IRP rabbit＇s rectal mucosa and submucosa to simulate two kinds of forces with the same strength but in different directions which were applied on the rectal mucous. One force was vertical downward, while the other was parallel to the direction of the rectal mucous. The different nodes of the level with relatively obvious mucosal prolapse were taken as observed objects to calculate the displacement of nodes. Results Young＇s elastic modulus of the rabbit＇s rectal mucosa and submucosa was （4.088 8±0. 1 61 5） MPa, and the Poisson＇s ratio was 0.470 0±0.005 0, and the elastic shear modulus was （1.390 9±0.059 5） MPa. These data were inputted into the finite element model of rabbit＇s anorectum. No significant differences were found in the displacement of the rectal ventral node 848 and node 850 between these two kinds of forces （P〉0.1）. However, significant differences were found in the displacement of rectal middle node 852, and dorsal node 854 and node 856 （P〈0.05）. Conclusion The displacement of rabbit＇s rectal mucosa is affected by the forced direction, which means the different forced directions may affect the bowel movement.
出处
《中国医学物理学杂志》
CSCD
2015年第6期781-784,共4页
Chinese Journal of Medical Physics
基金
国家自然科学基金(81173272)
福建省自然科学基金(2015J01402)
关键词
直肠
黏膜
位移量
有限元
受力方向
节点
模拟分析
rectum
mucosa
displacement
finite element
forced direction
node
simulation analysis
