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雌激素及其受体与肺癌的研究进展 被引量:1

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摘要 肺癌是目前世界上发病率和死亡率最高、预后性最差的恶性肿瘤之一,严重影响人类的健康和生存质量。过去的数10年里,研究人员普遍认为肺癌主要与吸烟、职业病、化学药品和环境污染等因素有关。近年研究显示,男性的肺癌发病率和死亡率正缓慢下降,而女性的肺癌发病率和死亡率却呈上升趋势。实验和流行病学研究均显示,雌激素可能参与了肺癌的形成。简要介绍了近期关于雌激素、雌激素受体和芳香化酶与肺癌相关的研究进展。
出处 《生物学通报》 2015年第11期1-4,共4页 Bulletin of Biology
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  • 1Slatore C. G., Chien J. W., Au D. H., et al. Lung cancer and hormone replacement therapy: association in the vitamins and lifestyle study. Journal of Clinical Oncology, 2010, 28(9): 1540-- 1546.
  • 2Clauge J., Reynolds P., Sullivan-Halley J., et al. Menopausal hormone therapy does not influence lung cancer risk: results from the California teacher study. Cancer Epidemiology, Bio- markers & Prevention, 2011,20(3):560--564.
  • 3Pestori A. C., Carugno M., Conconni D., et al. Hormone use and risk for lung cancer: a pooled analysis from the internat- ional Lung Cancer Consotrium (ILCCO). British Journal of Cancer, 2013,109(7):1954--1964.
  • 4Ganti A. K., Sahmoun A. E., Panwalkar A. W., et al. Horm- one replacement therapy is associated with decreased survival in women with lung cancer. Journal of Clinical Oncology,2006,24( 1 ):59--63.
  • 5Bouchardy C., Benhamou S., Schaffar R., eta/. Lung cancer mortality risk among breast cancer patients treated with antie- strogens. Cancer, 2011,117(6):1288--1295.
  • 6Xu X., Veenstra T. D.. Concentration of endogenous estrogens and estrogen metabolites in the NCI-60 human tumor cell lines. Genome Medicine, 2012,4 (4) :31.
  • 7Stabile L.P., Rothstein M. E., Cunningham D. E., eta/. Prevention of tobacco carcinogen-induced lung cancer in fem- ale mice using antiestrogens. Carcinogenesis, 2012, 33(11) 2181 --2189.
  • 8Mah V., Seligson D. B., Li A., eta/. Aromatase expression predicts survival in women with early-stage non-small cell lung cancer. Cancer Research, 2007,67 (21 ) : 10454-- 10490.
  • 9Chen Z., Zhang Y., Yang H., eta/. Estrogen promotes benzo [a]pyrene-induced lung carcinogenesis through exidative stress damage and cytochrome c-mediated caspase-3 activation pat- hways in female mile. Cancer Letter, 2011,308 ( 1 ) : 14--22.
  • 10Sethi S., Coti M., Lonardo F.. Expression of estrogen recep- tor beta 1 but not estrogen receptor beta 2 or alpha is linked to worse prognosis in stage I adenocarcinoma, in woman,in a large epidemiological cohort but not in a smaller, single hos-pital based series. United States and Canadian Academy of pathology, 2010,Abstract 1843.

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